130658-67-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(1-Pyridinyl-piperidin-4-yl)-methanol is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with unique therapeutic properties. Its structural features allow for the creation of complex molecules that can target specific biological pathways.
Used in Agrochemical Synthesis:
In the agrochemical industry, (1-Pyridinyl-piperidin-4-yl)-methanol is utilized as a building block for the development of new agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness and selectivity of these compounds in agricultural applications.
Used in Medicinal Chemistry:
(1-Pyridinyl-piperidin-4-yl)-methanol is employed as a structural component in medicinal chemistry for its potential to be incorporated into molecules with novel biological activities. Its unique structure can be leveraged to design compounds that interact with specific targets in the body, leading to the development of new therapeutic agents.
Used in Drug Development:
In drug development, (1-Pyridinyl-piperidin-4-yl)-methanol serves as a valuable precursor for the creation of advanced drug candidates. Its incorporation into drug molecules can lead to improved pharmacokinetic and pharmacodynamic properties, enhancing the overall efficacy and safety of new medications.
Used in Organic Synthesis:
As a building block in organic synthesis, (1-Pyridinyl-piperidin-4-yl)-methanol is used to construct more complex organic molecules for various applications. Its versatility in forming different types of chemical bonds allows for the synthesis of a wide range of compounds with diverse properties and functions.
Overall, (1-Pyridinyl-piperidin-4-yl)-methanol has a broad spectrum of potential uses in the field of chemistry and biotechnology, making it a valuable compound for researchers and industry professionals alike.

Upstream product

• 121912-29-6 1-(pyridin-4-yl)piperidine-4-carboxylic acid ethyl ester 
• 93913-86-1 4-carboxy-N-(4'-pyridino) piperidine 
• 219493-02-4 methyl N-(pyridin-4-yl)isonipecotate 
• 868-18-8 sodium tartrate 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 1126-09-6 4-carbethoxypiperidine 

Downstream Products

• 219491-85-7 2-Nitro-N-[1-(pyridin-4-yl)piperidin-4-ylmethoxycarbonyl)benzeneamine 
• 219508-26-6 N-(1-boc-6-indolyl)-2-[1-(4-pyridyl)piperidin-4-yl-methoxycarbonylamino]-4-nitrobenzamide 
• 219492-86-1 2-[1-(pyridin-4-yl)piperidin-4-ylmethylaminocarbonyl]amino-nitrobenzene 
• 219492-87-2 N₁-[1-(pyridin-4-yl)piperidin-4-ylmethylaminocarbonyl)-1,2-benzenediamine 
• 229646-37-1 4-(6-chloronaphthalen-2-ylsulfonyl)-1-[1-(pyridin-4-yl)piperidin-4-ylmethyl]piperazin-2-one 
• 229646-76-8 (S)-4-[(6-chloro-2-naphthalenyl)sulfonyl]-6-oxo-1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]-2-piperazinecarboxylic acid monohydrate 
• 229646-76-8 (R)-4-[(6-chloro-2-naphthalenyl)sulfonyl]-6-oxo-1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]-2-piperazinecarbocylic acid 
• 229646-52-0 4-[(6-chloro-2-naphthalenyl)sulfonyl]-6-oxo-1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]-2-piperazinecarboxylic acid 
• 219491-86-8 N₁-[[1-(4-pyridyl)piperidin-4-yl]methoxycarbonyl]-1,2-benzenediamine 

Relevant academic research and scientific papers

AMIDINE DERIVATIVE

Provision of a novel amidine derivative or a pharmaceutically acceptable salt thereof having an activated blood coagulation factor X-inhibitory activity. A compound represented by the formula (I) wherein each symbol is as defined above, or a pharmaceutically acceptable salt thereof.

Investigation of factor Xa inhibitors containing non-amidine S1 elements

Several non-amidino S1 derivatives of the 1,2-diaminobenzene-based scaffold (4) were synthesized and evaluated for their ability to bind to the active site and inhibit the human protease factor Xa. A subset of these compounds were also evaluated for their

Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring

A series of novel 2,7-disubstituted tetrahydroisoquinoline derivatives were designed and synthesized. Among these derivatives, compounds 1 and 2 exhibited potent inhibitory activity against factor Xa (FXa) and good selectivity with respect to other serine

AROMATIC AMIDES

This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Antithrombotic amides

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermidates thereof.

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen

HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA

This application relates to heteroaromatic amides (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Antithrombotic agents

This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

AROMATIC COMPOUNDS HAVING CYCLIC AMINO OR SALTS THEREOF

Compounds represented by general formula (I) or salts thereof which specifically inhibit FXa, exert a potent anticoagulant effect and thus are useful as medicinal compositions, wherein G1 to G4, X and Y represent each CH or N; Z1 represents -SO2- or -CH2 -; Q represents aryl or heteroaryl; and R1 to R9 represent each hydrogen or a substituent.