130694-68-7

Upstream product

• 67-56-1 methanol 
• 143-33-9 sodium cyanide 
• 130694-67-6 (-)-4(1E,3Z)-(4S,5R)-4-hydroxy-4-(3-methyl-5-oxo-1,3-pentadienyl)-3,3,5-trimethylcyclohexanone 
• 21293-29-8 (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentadienoic acid 
• 20548-02-1 (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one 
• 60046-49-3 (6R)-levodione 
• 130583-95-8 (4R,6R)-4-[(tert-butyldimethylsilyl)oxy]-2,2,6-trimethylcyclohexan-1-one 
• 130694-66-5 (-)-4(1E,3Z)-(4S,5R)-4-hydroxy-4-(5-hydroxy-3-methyl-1,3-pentadienyl)-3,3,5-trimethylcyclohexanone 
• 130694-57-4 (-)-4(Z)-(4R,5R)-4-hydroxy-4-(5-hydroxy-3-methylpent-3-en-1-ynyl)-3,3,5-trimethylcyclohexanone 
• 130583-96-9 Acetic acid (Z)-5-[(4R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-2,2,6-trimethyl-cyclohexyl]-3-methyl-pent-2-en-4-ynyl ester 
• 130584-04-2 (4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-((Z)-5-hydroxy-3-methyl-pent-3-en-1-ynyl)-2,2,6-trimethyl-cyclohexanol 
• 130694-64-3 (-)-9(Z)-(9R,10R)-9-(5-hydroxy-3-methylpent-3-en-1-ynyl)-3,3,8,8,10-pentamethyl-1,5-dioxaspiro<5,5>undecan-9-ol 
• 130646-73-0 (-)-1(Z)-(1R,4R,6R)-1-(5-acetoxy-3-methylpent-3-en-1-ynyl)-2,2,6-trimethylcyclohexan-1,4-diol 
• 130694-65-4 (-)-9(1E,3Z)-(9S,10R)-9-(5-hydroxy-3-methyl-1,3-pentadienyl)-3,3,8,8,10-pentamethyl-1,5-dioxaspiro<5,5>undecan-9-ol 

Downstream Products

• 130696-65-0 (-)-(4S,5R)-dihydroabscisic acid 

Relevant academic research and scientific papers

Synthesis of optically active cyclohexanone analogs of the plant hormone abscisic acid

The abscisic acid analogs (-)-(4R,5R)-, (+)-(4S,5S)-, and (-)-(4S,5R)-4(1E,3Z)-4-(4-carboxy-3-methyl-1,3-butadienyl)-4-hydroxy-3,3,5-trimethylcyclohexanones (dihydroabscisic acids), and (-)-(4S,5R)-, (+)-(4R,5S)-, and (-)-(4R,5R)-4(Z)-4-hydroxy-4-(5-hydroxy-3-methylpent-3-en-1-ynyl)-3,3,5-trimethylcyclohexanones were synthesized from a common precursor, (-)-(6R)-2,2,6-trimethylcyclohexan-1,4-dione, which was readily prepared by the fermentation of oxoisophorone with bakers' yeast.

Enantioselective Reduction of Racemic Abscisic Acid by Aspergillus niger Cultures

Biotransformation of racemic abscisic acid 1a with cultures of Aspergillus niger gives rise to the enantioselective reduction of the (S)-enantiomer to afford the corresponding (1'S,2'R)-(-)-2',3'-dihydro-ABA acid 2a in high enantiomeric excess (e.e.).The structure, stereochemistry, and preferred conformation of compound 2a have been elucidated on the basis of NMR evidence.