130697-91-5

Upstream product

• 118993-48-9 (3aS,7aR)-3a,7a-Dihydro-benzo[1,3]dioxol-2-one 
• 119043-06-0 (3aα,6α,7α,7aα)-6,7-epoxy-3a,6,7,7a-tetrahydrobenzo-1,3-dioxol-2-one 
• 100-39-0 benzyl bromide 
• 130641-48-4 <3aS-<3aα,4α,5β(R),7aα>>-3a,4,5,7a-tetrahydro-4-hydroxy-5-(1-phenylethoxy)benzo-1,3-dioxol-2-one 
• 134003-00-2 Toluene-4-sulfonic acid 2-hydroxy-1-phenyl-ethyl ester 
• 17199-29-0 (S)-Mandelic acid 
• 17793-95-2 cis-1,2-dihydrocatechol 
• 1517-69-7 (R)-1-phenylethanol 
• 130641-50-8 <3aR-<3aα,6α(R),7β,7aα>>-7-benzyloxy-3a,6,7,7a-tetrahydro-6-(1-phenylethoxy)benzo-1,3-dioxol-2-one 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 

Downstream Products

• 130633-29-3 <5(R)>-L-4-O-benzyl-2,3-O-isopropylidene-6-O-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>-5-O-(phenylethyl)-myo-inositol 
• 2068-89-5 myo-inositol 1,4,5-trisphosphate 
• 130633-27-1 <3aS-<3aα,4α,5β(R),6β,7β,7aα>>-4-benzyloxy-6,7-epoxy-5-(1-phenylethoxy)-hexahydro-2,2-dimethylbenzo-1,3-dioxole 
• 119525-96-1 L-6-O-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>-2,3-O-isopropylidene-myo-inositol 1,4,5-tris(dibenzylphosphate) 
• 130633-26-0 <1S-<1α,2α,3β,4α(R),5α,6α>>-3-benzyloxy-5,6-epoxy-4-(1-phenylethoxy)cyclohexane-1,2-diol 

Relevant academic research and scientific papers

MICROBIAL OXIDATION IN SYNTHESIS: PREPARATION OF MYO-INOSITOL PHOSPHATES AND RELATED CYCLITOL DERIVATIVES FROM BENZENE.

Pseudomonas putida oxidation of benzene affords cis-3,5-cyclohexadiene-1,2-diol (2) which is used as a novel precursor for the synthesis of D- and L-myo-inositol 1,4,5-triphosphates, (-)-(1) and (+)-(1).The versatility of this approach to functionalised cyclitols is illustrated in the synthesis of myo-inositol 1-phosphate (19), 6-deoxy, 6-deoxy-6-fluoro, and 6-deoxy-6-methyl myo-inositols (31), (37) and (43), and their 1,4,5-trisphosphate derivatives (33), (39) and (45).