130721-59-4Relevant articles and documents
Synthesis of N-substituted-4-methylene-oxazolidinones via base-catalyzed cyclization of propargylic alcohols with p-toluenesulfonyl isocyanate
Pi, Shao-Feng,Guo, Yue-Meng,Zhou, Zheng-Rui,Sun, Han-Zhou,Yi, Bing
, p. 521 - 523 (2020)
A practical method is developed for the synthesis of oxazolidinone derivatives, an important class of heterocyclic compounds. The effect of bases and solvents on this cyclization reaction is discussed and a simple new base–solvent system (triethylamine in toluene) is found to be the most effective. The reaction conditions developed here are mild and no by-products are observed. Moreover, using optimized conditions, a number of differently substituted propargylic alcohols are cyclized to the corresponding N-substituted-4-methylene-oxazolidinones in yields of up to 99%.
Efficient 1,3-Oxazolidin-2-one Synthesis through Heterogeneous PdII-Catalyzed Intramolecular Hydroamination of Propargylic Carbamates
Oschmann, Michael,Placais, Clotilde,Nagendiran, Anuja,B?ckvall, Jan-E.,Verho, Oscar
supporting information, p. 6295 - 6299 (2019/05/08)
Herein, we present an operationally simple protocol for the cycloisomerization of propargylic carbamates in which a heterogeneous catalyst consisting of Pd species immobilized on amino-functionalized siliceous mesocellular foam (PdII-AmP-MCF) i
Ruthenium Complex-catalyzed domino addition/exo- cycloisomerization of propargylic alcohols and tosyl isocyanate to form oxazolidinones
Li, Deng Yuan,Chen, Hao Jie,Liu, Pei Nian
supporting information, p. 1193 - 1198 (2015/04/22)
A ruthenium complex with a tetradentate nitrogen-phosphorus mixed ligand is shown to be an efficient catalyst for domino addition/exo-cycloisomerization of propargylic alcohols and tosyl isocyanate. In the presence of 2-5 mol% ruthenium complex, a range o
