130749-22-3Relevant academic research and scientific papers
Tris(benzotriazol-1-yl)methane: A -CO2H Synthon for the Preparation of Carboxylic Acids
Katritzky, Alan R.,Yang, Zhijun,Lam, Jamshed N.
, p. 666 - 669 (2007/10/02)
Lithiation of tris(benzotriazol-1-yl)methane 16 gives the tris(benzotriazolyl)methyl carbanion 17 which affords substitution products 18 with many electrophiles.Acidic hydrolysis of 18 affords the corresponding carboxylic acids 19 in good yield.The syntheses of several α-functionalized carboxylic acids are described.
