130856-90-5Relevant articles and documents
Synthesis of 2-hydroxytetrahydrofurans by Wacker-type oxidation of 1,1-disubstituted alkenes
Kataoka, Yasutaka,Komori, Saki,Shimizu, Yuhei,Tanaka, Rina,Ura, Yasuyuki
, p. 570 - 574 (2022/02/02)
1,1-Disubstituted alkenes feature high steric hindrance, which renders their Wacker-type oxidation difficult. We demonstrate the stereoselective synthesis of 2-hydroxytetrahydrofurans via the Wacker-type oxidation of 3-methyl-3-buten-1-ols by using a PdCl
Enzyme-Inspired Chiral Secondary-Phosphine-Oxide Ligand with Dual Noncovalent Interactions for Asymmetric Hydrogenation
Chen, Caiyou,Zhang, Zhefan,Jin, Shicheng,Fan, Xiangru,Geng, Mingyu,Zhou, Yan,Wen, Songwei,Wang, Xinrui,Chung, Lung Wa,Dong, Xiu-Qin,Zhang, Xumu
, p. 6808 - 6812 (2017/06/06)
Inspired by the unique character of enzymes, we developed novel chiral SPO (secondary-phosphine-oxide) ligand (SPO-Wudaphos) which can enter into both ion pair and H-bond noncovalent interactions. The novel chiral SPO-Wudaphos exhibited excellent results
An enantioselective synthesis of the C3-C21 segment of the macrolide immunosuppressive agent FR252921
Ghosh, Arun K.,Rodriguez, Samuel
supporting information, p. 2884 - 2887 (2016/06/14)
An enantioselective synthesis of the C3-C21 segment of the novel immunosuppressant FR252921 is described. The C12 and C13 stereogenic centers were constructed by a non-aldol process utilizing optically active 4-phenylbutyrolactone. The C18 stereogenic cen