130879-97-9Relevant articles and documents
Silicate anion-stabilized layered magnesium-aluminium hydrotalcite
Baskaran, Thangaraj,Kumaravel, Raju,Christopher, Jayaraj,Sakthivel, Ayyamperumal
, p. 16392 - 16398 (2013)
Layered magnesium-aluminum hydrotalcite (HT) were completely intercalated and stabilized with silicate anions. The silicate anion-stabilized HT retained the layered structure and possessed a high surface area of 530-540 m2 g-1 with needle-like particles 60 nm × 4 nm in dimension. The findings of FT-IR, powder XRD, TGA, DSC and 29Si MAS-NMR revealed that silicate anions were intercalated and coated on the surface of layered HTs with the formation of a solid solution of magnesium silicate and HT. The resultant silicate-anion-intercalated materials are found to be promising catalysts for the synthesis of 1-phenoxy-2-propanol using phenol with propylene oxide. The Royal Society of Chemistry 2013.
Resolution of 1-phenoxy-, 1-phenylmethoxy- and 1-(2-phenylethoxy)-2-propanol and their butanoates by hydrolysis with lipase B from Candida antarctica
Hoff, Bard H.,Waagen, Viggo,Anthonsen, Thorleif
, p. 3181 - 3186 (1996)
Resolutions of butanoic esters of 1-phenoxy-2-propanol, 1-phenylmethoxy-2-propanol and 1-(2-phenylethoxy)-2-propanol have been studied with four different lipases as catalysts. Using lipase B from Candida antarctica very high enantiomer ratios were obtained. These substrate-lipase pairs represent an excellent way of getting enantiomerically pure protected 1,2-propanediols in high chemical yield. Copyright (C) Elsevier Science Ltd.
Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution
Li, Guangyue,Maria-Solano, Miguel A.,Romero-Rivera, Adrian,Osuna, Sílvia,Reetz, Manfred T.
, p. 9454 - 9457 (2017)
The long-standing problem of achieving high activity of a thermophilic enzyme at low temperatures and short reaction times with little tradeoff in thermostability has been solved by directed evolution, an alcohol dehydrogenase found in hot springs serving as the catalyst in enantioselective ketone reductions.
Regiodivergent Reductive Opening of Epoxides by Catalytic Hydrogenation Promoted by a (Cyclopentadienone)iron Complex
De Vries, Johannes G.,Gandini, Tommaso,Gennari, Cesare,Jiao, Haijun,Pignataro, Luca,Stadler, Bernhard M.,Tadiello, Laura,Tin, Sergey
, p. 235 - 246 (2022/01/03)
The reductive opening of epoxides represents an attractive method for the synthesis of alcohols, but its potential application is limited by the use of stoichiometric amounts of metal hydride reducing agents (e.g., LiAlH4). For this reason, the corresponding homogeneous catalytic version with H2 is receiving increasing attention. However, investigation of this alternative has just begun, and several issues are still present, such as the use of noble metals/expensive ligands, high catalytic loading, and poor regioselectivity. Herein, we describe the use of a cheap and easy-To-handle (cyclopentadienone)iron complex (1a), previously developed by some of us, as a precatalyst for the reductive opening of epoxides with H2. While aryl epoxides smoothly reacted to afford linear alcohols, aliphatic epoxides turned out to be particularly challenging, requiring the presence of a Lewis acid cocatalyst. Remarkably, we found that it is possible to steer the regioselectivity with a careful choice of Lewis acid. A series of deuterium labeling and computational studies were run to investigate the reaction mechanism, which seems to involve more than a single pathway.
CATALYST FOR PREPARING PROPYLENE GLYCOL PHENYL ETHER AND METHOD FOR SYNTHESIZING PROPYLENE GLYCOL PHENYL ETHER
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Paragraph 0022-0049, (2020/06/08)
Disclosed is a method for preparing propylene glycol phenyl ether, comprising carrying out a polymerization reaction of phenol and a propylene oxide in the presence of a quaternary phosphonium salt compound as a catalyst. Preferably, the method comprises mixing phenol and a quaternary phosphonium salt compound, and then adding propylene oxide under oxygen-free conditions, wherein the phenol is polymerized with the propylene oxide to produce the propylene glycol phenyl ether. The propylene glycol phenyl ether thus prepared has few impurities and contains no metal ions, such as potassium and sodium, and does not require subsequent operations to remove metal ions and perform rectification separation, thereby reducing the costs and allowing same to be directly applied to high-standard industrial production.
Preparation methods and applications of chiral spirophosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof
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Paragraph 0265-0272, (2020/08/18)
The invention relates to preparation methods and applications of a chiral spirophosphine-nitrogen-phosphine tridentate ligand SpiroPNP and an iridium catalyst Ir-SpiroPNP thereof. The chiral spirophosphine-nitrogen-phosphine tridentate ligand is a compound represented by a formula I, or a racemate or an optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly structurallycharacterized by having a chiral spiro indane skeleton and a phosphine ligand with a large steric hindrance substituent. The chiral spirophosphine-nitrogen-phosphine tridentate ligand can be synthesized by taking a 7-diaryl/alkylphosphino-7'-amino-1,1'-spiro indane compound with a spiro skeleton as a chiral starting raw material. The iridium catalyst of the chiral spirophosphine-nitrogen-phosphinetridentate ligand is a compound represented by a formula II which is described in the specification, or a raceme or an optical isomer, or a catalytically acceptable salt thereof, can be used for catalyzing asymmetric catalytic hydrogenation reaction of carbonyl compounds, particularly shows high yield (greater than 99%) and enantioselectivity (as high as 99.8% ee) in asymmetric hydrogenation reaction of simple dialkyl ketone, and has practical value.
