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CAS

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1308889-53-3

benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1308889-53-3 Structure

  • Basic information

    1. Product Name: benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate
    2. Synonyms: benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate
    3. CAS NO:1308889-53-3
    4. Molecular Formula:
    5. Molecular Weight: 440.496
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1308889-53-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate(CAS DataBase Reference)
    10. NIST Chemistry Reference: benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate(1308889-53-3)
    11. EPA Substance Registry System: benzyl 7-(3-(dimethylamino)propoxy)-6-methoxy-8-methyl-2-oxo-2H-chromen-3-ylcarbamate(1308889-53-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1308889-53-3(Hazardous Substances Data)

1308889-53-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1308889-53-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,8,8,8 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1308889-53:
(9*1)+(8*3)+(7*0)+(6*8)+(5*8)+(4*8)+(3*9)+(2*5)+(1*3)=193
193 % 10 = 3
So 1308889-53-3 is a valid CAS Registry Number.

1308889-53-3Relevant articles and documents

Engineering an antibiotic to fight cancer: Optimization of the novobiocin scaffold to produce anti-proliferative agents

Zhao, Huiping,Donnelly, Alison C.,Kusuma, Bhaskar R.,Brandt, Gary E. L.,Brown, Douglas,Rajewski, Roger A.,Vielhauer, George,Holzbeierlein, Jeffrey,Cohen, Mark S.,Blagg, Brian S. J.

, p. 3839 - 3853 (2011)

Development of the DNA gyrase inhibitor, novobiocin, into a selective Hsp90 inhibitor was accomplished through structural modifications to the amide side chain, coumarin ring, and sugar moiety. These species exhibit ?700- fold improved anti-proliferative activity versus the natural product as evaluated by cellular efficacies against breast, colon, prostate, lung, and other cancer cell lines. Utilization of structure- activity relationships established for three novobiocin synthons produced optimized scaffolds, which manifest midnanomolar activity against a panel of cancer cell lines and serve as lead compounds that manifest their activities through Hsp90 inhibition.

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