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1309608-05-6

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1309608-05-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1309608-05-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,9,6,0 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1309608-05:
(9*1)+(8*3)+(7*0)+(6*9)+(5*6)+(4*0)+(3*8)+(2*0)+(1*5)=146
146 % 10 = 6
So 1309608-05-6 is a valid CAS Registry Number.

1309608-05-6Relevant articles and documents

Identification and initial SAR of silybin: An Hsp90 inhibitor

Zhao, Huiping,Brandt, Gary E.,Galam, Lakshmi,Matts, Robert L.,Blagg, Brian S.J.

, p. 2659 - 2664 (2011)

Through Hsp90-dependent firefly luciferase refolding and Hsp90-dependent heme-regulated eIF2α kinase (HRI) activation assays, silybin was identified as a novel Hsp90 inhibitor. Subsequently, a library of silybin analogues was designed, synthesized and evaluated. Initial SAR studies identified the essential, non-essential and detrimental functionalities on silybin that contribute to Hsp90 inhibition.

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