130972-80-4

Upstream product

• 592-41-6 1-hexene 
• 56762-00-6 methyl-butyl ether 
• 130972-94-0 N-[4-(2-Phthalimidoethoxy)-3-methoxybenzyl]-N'-[2-(4-chlorophenyl)ethyl]thiourea 
• 130972-90-6 tert-butyl N-[4-(2-bromoethoxy)-3-methoxybenzyl]carbamate 
• 130972-89-3 (4-hydroxy-3-methoxybenzyl)carbamic acid tert-butyl ester 
• 7149-10-2 vanillylamine hydrochloride 
• 17608-10-5 2-(4-chlorophenyl)ethyl isothiocyanate 
• 130972-91-7 {4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-3-methoxy-benzyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Analogues of capsaicin with agonist activity as novel analgesic agents: Structure-activity studies. 4. Potent, orally active analgesics

Structural features of three regions of the capsaicin molecule necessary for agonist properties were delineated by a previously reported modular approach. These in vitro agonist effects were shown to correlate with analgesic potency in rodent models. Comb

Capsaicin derivatives

Novel capsaicin derivatives of general formula I STR1 wherein R, R1 to R7 and X may be a variety of substituents, processes for the production thereof, pharmaceutical compositions containing them and use thereof as pharmaceuticals.