13100-82-8

Basic information

• Product Name: CYSTEIC ACID
• Synonyms: 2-Amino-3-sulfopropionic acid;α-Amino-β-sulfopropionic acid;3-Sulfoalanine;DL-Alanine, 3-sulfo-
• CAS NO: 13100-82-8
• Molecular Formula: C₃H₇NO₅S
• Molecular Weight: 169.16
• EINECS: 207-861-3
• Mol File: 13100-82-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Density: 1.433 (estimate)
• Refractive Index: 1.5130 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 0.68±0.50(Predicted)
• CAS DataBase Reference: CYSTEIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: CYSTEIC ACID(13100-82-8)
• EPA Substance Registry System: CYSTEIC ACID(13100-82-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 13100-82-8(Hazardous Substances Data)

Usage

Uses

3-Sulfoalanine,

Definition

ChEBI: An amino sulfonic acid that is the sulfonic acid analogue of cysteine.

Purification Methods

Likely impurities are cystine and oxides of cysteine. Crystallise the acid from water by adding 2 volumes of EtOH. It crystallises from H2O as the monohydrate. When recrystallised from aqueous MeOH it has m 264-266o, and the anhydrous acid has m ~260o(dec). [Chapeville & Formageot Biochim Biophys Acta 26 538 1957, Gortner & Hoffman J Biol Chem 72 435 1927, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p1908 1961.]

InChI:InChI=1/C3H7NO5S/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m1/s1

Upstream product

• 56-89-3 L-cystine 
• 98022-26-5 sulfo-pyruvic acid 
• 921-01-7 rac-cysteine 
• 616-91-1 N-acetylcystein 
• 498-40-8 L-Cysteic acid 
• 7647-01-0 hydrogenchloride 
• 7553-56-2 iodine 
• 7732-18-5 water 
• 59-51-8 DL-methionine 
• 101872-01-9 4-benzoylamino-1,1-dioxo-1λ⁶-isothiazolidin-3-one 
• 56-89-3 cysteine disulfide 
• 52-90-4 L-Cysteine 

Downstream Products

• 107-35-7 Tau 
• 99691-25-5 2-amino-3-phenacyloxysulfonyl-propionic acid phenacyl ester 
• 959396-49-7 C₂₃H₂₀N₄O₉S 
• 1315319-49-3 N-(m-toluoyl)cysteic acid 
• 1315319-51-7 N-(4-methoxybenzoyl)-L-cysteic acid 
• 302-84-1 serin 

Relevant articles and documents

The radiation chemistry of biochemical disulfides. I. The low-dose x-radiolysis of cystine.

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GLUCAGON ANALOGS EXHIBITING ENHANCED SOLUBILITY IN PHYSIOLOGICAL pH BUFFERS

Modified glucagon peptides are disclosed having improved solubility while retaining glucagon agonist activity. The glycogen peptides have been modified by substitution of native amino acids with, and/or addition of, charged amino acids to the carboxy terminus of the peptide. The modified glucagon agonists can be further modified by pegylation, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 23, or both to further enhance the solubility of the glucagon agonist analogs.

Glutamate 2,3-aminomutases and methods of use thereof

There are provided nucleic acids, including isolated DNA molecules, which encode glutamate 2,3-aminomutase enzymes, polypeptides produced from such nucleic acids and methods of making the nucleic acids and polypeptides. There are further provided methods of producing β-glutamate from glutamate using glutamate 2,3-aminomutase.