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1310486-30-6

1310486-30-6

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1310486-30-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1310486-30-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,4,8 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1310486-30:
(9*1)+(8*3)+(7*1)+(6*0)+(5*4)+(4*8)+(3*6)+(2*3)+(1*0)=116
116 % 10 = 6
So 1310486-30-6 is a valid CAS Registry Number.

1310486-30-6Downstream Products

1310486-30-6Relevant articles and documents

Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists

Lamb, Jeffrey P.,Engers, Darren W.,Niswender, Colleen M.,Rodriguez, Alice L.,Venable, Daryl F.,Conn, Jeffrey P.,Lindsley, Craig W.

, p. 2711 - 2714 (2011/06/20)

This Letter describes a chemical lead optimization campaign directed at a weak mGlu5 NAM discovered while developing SAR for the mGlu 5 PAM, ADX-47273. An iterative parallel synthesis effort discovered multiple, subtle molecular switches that afford potent mGlu5 NAMs, mGlu5 PAMs as well as mGlu5 partial antagonists.

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