29458-38-6

Basic information

• Product Name: 6-METHOXYURACIL
• Synonyms: SPECS AE-848/30739014;6-METHOXYURACIL;2,4(1H,3H)-Pyrimidinedione, 6-methoxy- (9CI);2,4-Dihydroxy-6-methoxypyrimidine;6-MethoxypyriMidine-2,4(1H,3H)-dione
• CAS NO: 29458-38-6
• Molecular Formula: C₅H₆N₂O₃
• Molecular Weight: 142.11
• Product Categories: PYRIMIDINE;Pyridines, Pyrimidines, Purines and Pteredines
• Mol File: 29458-38-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 204-206 °C
• Appearance: /
• Density: 1.39 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.74±0.10(Predicted)
• CAS DataBase Reference: 6-METHOXYURACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXYURACIL(29458-38-6)
• EPA Substance Registry System: 6-METHOXYURACIL(29458-38-6)

Safety Data

• Hazardous Substances Data: 29458-38-6(Hazardous Substances Data)

Usage

General Description

6-Methoxyuracil is a chemical compound and a methylated derivative of uracil. It is a purine analogue that has a methoxy group attached to the 6-position of the uracil ring. 6-METHOXYURACIL is used in the synthesis of antiviral and anticancer drugs due to its ability to interfere with nucleic acid replication. It has also been studied for its potential as a fluorescent probe for nucleic acid detection. Additionally, 6-Methoxyuracil has been used in the development of photoresponsive materials and as a building block in organic synthesis. Overall, 6-Methoxyuracil has a variety of applications in the fields of pharmaceuticals, materials science, and organic chemistry.

Upstream product

• 67-56-1 methanol 
• 67-52-7 pyrimidine-2,4,6-triol 
• 67-52-7 BARBITURIC ACID 
• 121-45-9 phosphorous acid trimethyl ester 
• 186581-53-3 diazomethane 

Downstream Products

• 36161-39-4 1-methyl-6-methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine 
• 147917-42-8 (3-Benzyl-4-methoxy-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl)-acetic acid methyl ester 
• 147917-37-1 1-Benzyl-6-methoxy-1H-pyrimidine-2,4-dione 
• 13106-85-9 2,4,6-trimethoxypyrimidine 
• 52119-20-7 1-methyl-4,6-dimethoxy-2-oxo-1,2-dihydropyrimidine 
• 4097-20-5 6-methoxy-1,3-dimethyluracil 
• 36161-42-9 1-methyl-2,4-dimethoxy-6-oxo-1,6-dihydropyrimidine 
• 43212-41-5 2,4-dichloro-6-methoxypyrimidine 

Relevant articles and documents

One-pot synthesis of stable phosphorus ylides by three-component reaction between arylglyoxals, phosphines and barbituric or Meldrum’s acid

An efficient one-pot method for the synthesis of new substituted phosphorus ylides is described via three-component reaction between arylglyoxals, C–H acids such as barbituric acid and Meldrum’s acid and triphenylphosphine or tri-n-octylphosphine. This re

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.

PYRIMIDINE DERIVATIVES FOR THE INHIBITION OF IGF-IR TYROSINE KINASE ACTIVITY

A compound of formula (I) wherein the substituents are as defined in the text for use in inhibiting insulin-like growth factor 1 receptor activity in a warm blooded animal such as man.