131085-31-9

Upstream product

• 917-64-6 methyl magnesium iodide 
• 215251-69-7 4-(tert-butyldiphenylsilyloxy)-N-methoxy-N-methylbutanamide 
• 626-95-9 1,4-Pentanediol 
• 130372-07-5 4-(tret-butyldiphenylsilyloxy)butan-1-ol 
• 127793-62-8 4-((tert-butyldiphenylsilyl)oxy)butanal 
• 93547-88-7 t-butyl diphenylsilanol 
• 1071-73-4 5-Hydroxy-2-pentanone 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 5390-04-5 pent-1-yn-5-ol 
• 91266-03-4 tert-butyl-pent-4-ynyloxy-diphenyl-silane 
• 558465-78-4 (rac)-5-{[tert-butyl(diphenyl)silyl]oxy}pentan-2-ol 
• 81929-33-1 tert-Butyl-(4,4-dimethoxy-pentyloxy)-diphenyl-silane 

Downstream Products

• 131074-33-4 5-(tert-butyldiphenylsilyloxy)-2-methyl-2-(phenylsulfanyl)-pentanal 
• 152549-43-4 tert-butyl(4-methylpent-4-enyloxy)diphenylsilane 
• 445424-75-9 ethyl 6-(tert-butyldiphenylsilyloxy)-3-methylhex-2-enoate 
• 497931-30-3 5-t-butyldiphenylsiloxy-2-cyclopropylidenepentane 
• 1115390-00-5 C₂₅H₃₇NO₂SSi 
• 131074-45-8 Benzoic acid (2R,3R,4S)-7-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-2,4-dimethyl-4-phenylsulfanyl-heptyl ester 
• 131074-35-6 (2S,3S,4S)-7-(tert-Butyl-diphenyl-silanyloxy)-2,4-dimethyl-4-phenylsulfanyl-heptane-1,3-diol 
• 131074-35-6 (2R,3R,4S)-7-(tert-Butyl-diphenyl-silanyloxy)-2,4-dimethyl-4-phenylsulfanyl-heptane-1,3-diol 
• 131074-46-9 tert-Butyl-[3-((2S,3S,4R)-2,4-dimethyl-3-phenylsulfanyl-tetrahydro-furan-2-yl)-propoxy]-diphenyl-silane 
• 131074-46-9 tert-Butyl-[3-((2S,3R,4S)-2,4-dimethyl-3-phenylsulfanyl-tetrahydro-furan-2-yl)-propoxy]-diphenyl-silane 
• 131074-38-9 Benzoic acid (2R,3R,4S)-3,7-dihydroxy-2,4-dimethyl-4-phenylsulfanyl-heptyl ester 
• 131074-44-7 Benzoic acid (2S,3R)-2-methyl-3-((S)-2-methyl-tetrahydro-furan-2-yl)-3-phenylsulfanyl-propyl ester 
• 131074-37-8 (2R,3R,4S)-2,4-Dimethyl-4-phenylsulfanyl-heptane-1,3,7-triol 

Relevant academic research and scientific papers

Chemoselective deoxygenation of ether-substituted alcohols and carbonyl compounds by B(C6F5)3-catalyzed reduction with (HMe2SiCH2)2

B(C6F5)3-catalyzed deoxygenation of ether-substituted alcohols and carbonyl compounds has been developed using (HMe2SiCH2)2 as the reductant. This unique reagent shows distinct superiority over traditional one silicon-centered hydrosilanes, giving the corresponding alkanes in high yields with good tolerance of ethers, aryl halides and alkenes. The control experiments suggest that (HMe2SiCH2)2 might facilitate the approach in an intramolecular Si/O activation manner.

Functional Metathesis Catalyst Through Ring Closing Enyne Metathesis: One Pot Protocol for Living Heterotelechelic Polymers

Enyne ring closing metathesis has been used to synthesize functional group carrying metathesis catalysts from a commercial (Ru-benzylidene) Grubbs' catalysts. The new Grubbs-type ruthenium carbene was used to synthesize living heterotelechelic ROMP polymers without any intermediate purification. Olefin metathesis with a mono substituted alkyne followed by ring closing metathesis with an allylic ether provided efficient access to new functional group carrying metathesis catalysts. Different functional benzylidene and alkylidene derivatives have been investigated in the synthesis of heterotelechelic polymers in one pot.

PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Provided herein are compounds of formula (I) useful for the treatment of PPAR-delta related diseases (e.g. mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic diseases).

A Remarkably Simple Hybrid Surfactant-NHC Ligand, Its Gold-Complex, and Application in Micellar Catalysis

A combination of an N-heterocyclic carbene (NHC) ligand and a structurally simple surfactant has been realized, the hybrid surfactant-NHC. The related gold complex was synthesized, fully characterized, and applied in catalysis. This remarkably simple strategy allows, in combination with a co-surfactant, the application of gold catalysis in water. Just merge it! The hybrid of a surfactant and an N-heterocyclic carbene (NHC) ligand is reported and applied for the synthesis of the derived gold complex (see scheme). The new resulting NHC-based metallosurfactant can interact with surfactants to form micelles and allows micellar catalysis for gold catalysis in water.

Synthetic studies toward neovibsanins A and B: construction of the neovibsanin core utilizing palladium(0)-catalyzed carbonylative cyclization with carbon monoxide

The core A-ring of neovibsanins A (1) and B (2), which are potent neurotrophic agents isolated from the leaves of Viburnum awabuki, have been effectively constructed by the intramolecular palladium(0)-catalyzed carbonylative cyclization of alkenyl iodide

Diastereoselective ring-closing metathesis for the construction of a quaternary carbon stereogenic center

A diastereoselective ring-closing metathesis of the trienes 1 leading to the formation of a quaternary carbon stereogenic center on the cyclohexenes 2 has been developed.

Total synthesis of marine diterpenoid stolonidiol

Marine dolabellane diterpenoid stolonidiol was synthesized from L-ascorbic acid. The method for this total synthesis involves formation of the bicyclo[2.2.1]heptane derivative using a diastereoselective sequential Michael reaction, formation of cyclopentane derivative by the retro-aldol reaction and construction of an 11-membered carbocyclic ring through the intramolecular Horner-Wadsworth-Emmons reaction.

The scope and limitation of the [1,4]-SPh shift in the synthesis of allylic alcohols

Treatment of a series of 4-phenylsulfanyl-1,3-diols with toluene-p-sulfonyl chloride in pyridine gives stereospecifically substituted allylic alcohols in near quantitative yield via a [1,4]-SPh shift. We comment on the structural variation at both the mig