1311201-63-4Relevant academic research and scientific papers
Dynamic Kinetic Resolution of 3-Aryl-4-pentenoic Acids
Koszelewski, Dominik,Brodzka, Anna,Z?d?o, Anna,Paprocki, Daniel,Trzepizur, Damian,Zysk, Ma?gorzata,Ostaszewski, Ryszard
, p. 3287 - 3292 (2016)
The first example of dynamic kinetic resolution (DKR) of chiral unsaturated carboxylic acids is described. The application of tandem metal-enzyme DKR is a powerful tool for the manufacture of high-value chemical commodities. This new protocol of kinetic r
Studies on the chemoenzymatic synthesis of 3-phenyl-GABA and 4-phenyl-pyrrolid-2-one: The influence of donor of the alkoxy group on enantioselective esterification
Brodzka, Anna,Koszelewski, Dominik,Cwiklak, Malgorzata,Ostaszewski, Ryszard
, p. 427 - 433 (2013/07/19)
A new chemoenzymatic method for the synthesis of enantiomerically pure 3-phenyl-γ-aminobutyric acid 1 and 4-phenyl-pyrrolid-2-one 9 based on the enzymatic kinetic resolution of 3-phenyl-4-pentenoic acid 2 is described herein. Enzymatic resolution of the r
The studies on chemoenzymatic synthesis of Femoxetine
Brodzka, Anna,Koszelewski, Dominik,Ostaszewski, Ryszard
scheme or table, p. 96 - 101 (2012/09/25)
The studies on enzymatic kinetic resolution of 3-phenyl-4-pentenoic acid esters were performed. The obtained results demonstrated that the careful choice of biocatalyst and a reaction type are very important for successful enzymatic kinetic resolution. Ki
A chiral bidentate sp2-N ligand, naph-diPIM: Application to CpRu-catalyzed asymmetric dehydrative C-, N-, and O-allylation
Miyata, Kengo,Kutsuna, Hironori,Kawakami, Sho,Kitamura, Masato
, p. 4649 - 4653 (2011/06/27)
A handy new ligand: The CpRu complex (Cp=cyclopentadienyl) of a new type of chiral bisamidine ligand with a naphtho[1,2-b:7,8-b]dipyrroloimidazole (Naph-diPIM) skeleton with a Bronsted acid efficiently catalyzes dehydrative intermolecular C-allylation with high enantio- and regioselectivity. The catalytic system also gives nearly enantiomerically pure cycloalkanes and N- and O-heterocycles with a substrate/catalyst ratios of up to 10 000.
