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1311393-03-9

ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1311393-03-9 Structure

  • Basic information

    1. Product Name: ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate
    2. Synonyms: ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate
    3. CAS NO:1311393-03-9
    4. Molecular Formula:
    5. Molecular Weight: 472.624
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1311393-03-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate(1311393-03-9)
    11. EPA Substance Registry System: ethyl 2-(2,5-diphenethoxybenzylidene)hexanoate(1311393-03-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1311393-03-9(Hazardous Substances Data)

1311393-03-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1311393-03-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,1,3,9 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1311393-03:
(9*1)+(8*3)+(7*1)+(6*1)+(5*3)+(4*9)+(3*3)+(2*0)+(1*3)=109
109 % 10 = 9
So 1311393-03-9 is a valid CAS Registry Number.

1311393-03-9Relevant articles and documents

Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid

Hieke, Martina,Greiner, Christine,Dittrich, Michaela,Reisen, Felix,Schneider, Gisbert,Schubert-Zsilavecz, Manfred,Werz, Oliver

, p. 4490 - 4507 (2011/09/15)

Various inflammatory diseases are associated with the excessive formation of leukotrienes (LTs) and prostaglandins (PGs). Herein, we present a novel class of dual inhibitors of 5-lipoxygenase (5-LO) and microsomal prostaglandin E 2 synthase-1 (

SAR studies of acidic dual γ-secretase/PPARγ modulators

Hieke, Martina,Ness, Julia,Steri, Ramona,Greiner, Christine,Werz, Oliver,Schubert-Zsilavecz, Manfred,Weggen, Sascha,Zettl, Heiko

, p. 5372 - 5382 (2011/10/12)

A novel set of dual γ-secretase/PPARγ modulators characterized by a 2-benzyl hexanoic acid scaffold is presented. Synthetic efforts were focused on the variation of the substitution pattern of the central benzene. Finally, we obtained a new class of 2,5-disubstituted 2-benzylidene hexanoic acid derivatives, which act as dual γ-secretase/PPARγ modulators in the low micromolar range. We have explored broad SAR and successfully improved the dual pharmacological activity and the selectivity profile against potential off-targets such as NOTCH and COX. Compound 17 showed an IC50 Aβ42 = 2.4 μM and an EC50 PPARγ = 7.2 μM and could be a valuable tool to further evaluate the concept of dual γ-secretase/ PPARγ modulators in animal models of Alzheimer's disease.

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