4134-14-9Relevant articles and documents
Anionic versus photochemical diastereoselective deconjugation of diacetone D-glucose α,β-unsaturated esters
Bargiggia, Frederic,Piva, Olivier
, p. 1819 - 1827 (2003)
Deconjugation of diacetone D-glucose α,β-unsaturated esters has been conducted by deprotonation using NaHMDS with HMPA as co-solvent followed by stereoselective protonation at low temperature. High selectivities (>95%) were obtained with α-methyl linear compounds.
Structure optimization of a new class of PPARγ antagonists
Hernandez-Olmos, Victor,Knape, Tilo,Heering, Jan,von Knethen, Andreas,Kilu, Whitney,Kaiser, Astrid,Wurglics, Mario,Helmst?dter, Moritz,Merk, Daniel,Schubert-Zsilavecz, Manfred,Parnham, Michael J.,Steinhilber, Dieter,Proschak, Ewgenij
supporting information, (2019/09/30)
Peroxisome proliferator-activated receptor gamma (PPARγ) modulators have found wide application for the treatment of cancers, metabolic disorders and inflammatory diseases. Contrary to PPARγ agonists, PPARγ antagonists have been much less studied and alth
COMPETITIVE PPAR-GAMMA ANTAGONISTS
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Paragraph 24, (2016/05/10)
The present invention pertains to a new compound E)-2-(5-((4-methoxy-2- (trifluoromethyl)quinolin-6-yl)methoxy)-2-((4-(trifluoromethyl) benzyl)oxy)-benzylidene) hexanoic acid (MTTB), and its derivatives. The compounds of the invention are useful as select