1311463-07-6Relevant articles and documents
Bis-Alkoxycarbonylation of Acrylic Esters and Amides for the Synthesis of 2-Alkoxycarbonyl or 2-Carbamoyl Succinates
Olivieri, Diego,Tarroni, Riccardo,Della Ca', Nicola,Mancuso, Raffaella,Gabriele, Bartolo,Spadoni, Gilberto,Carfagna, Carla
, p. 533 - 544 (2020)
The first example of the bis-alkoxycarbonylation of acrylic esters and acrylic amides, leading to differently substituted 1,1,2-ethanetricarboxylate compounds and 2-carbamoylsuccinates respectively, is reported. The catalyst is formed in situ by mixing Pd
Regioselective Wacker oxidation of internal alkenes: Rapid access to functionalized ketones facilitated by cross-metathesis
Morandi, Bill,Wickens, Zachary K.,Grubbs, Robert H.
, p. 9751 - 9754 (2013/09/23)
Wacka wacka: The title reaction makes use of a wide range of directing groups (DG) to enable the highly regioselective oxidation of alkenes, and occurs predictably at the distal position. Both E and Z alkenes afford valuable functionalized ketones and cross-metathesis was shown to facilitate the preparation of the starting materials. BQ=benzoquinone. Copyright
