23433-05-8Relevant academic research and scientific papers
Aliphatic β-D-glucosides from fruits of Carica pubescens
Krajewski, Doris,Duque, Carmenza,Schreier, Peter
, p. 1627 - 1631 (1997)
Ethyl 3-O-β-D-glucopyranosylbutanoate, butyl 3-O-β-D- glucopyranosylbutanoate and 3-oxo-octyl 1-O-β-D-glucopyranoside were isolated from Carica pubescens fruit pulp by liquid chromatography on XAD. Identifications were performed after peracetylation by comparison of HRGC and HRGC-mass spectral data with those of synthesized reference compounds. Chiral evaluation of glycosidically-bound 3-hydroxybutanoates and octane-1,3-diol was achieved by multidimensional gas chromatography, combining a polar achiral column (DB-Wax) with a chiral main column (heptakis-2,6-di-O-methyl- 3-O-pentyl-β-cyclodextrin/OV 1701 and 2.3-di-O-acetyl-6-O-tert-butyl- dimethylsilyl-β-cyclodextrin/OV 1701, respectively). Comparison of retention times of synthesized, optically-enriched reference compounds with enzymically-released aglycones revealed enantiomeric excesses of the (S)-3- hydroxybutanoates, i.e. 96% and 24%, for the ethyl and the butyl ester, respectively. Octane-1,3-diol exhibited an enantiomeric excess of (R)-90%.
IDENTIFICATION OF 3-HYDROXYOCTYL β-D-GLUCOSIDE AND ABSOLUTE CONFIGURATION OF FREE AND BOUND OCTANE-1,3-DIOL IN APPLE FRUIT
Schwab, Wilfried,Scheller, Gerhard,Gerlach, Doris,Schreier, Peter
, p. 157 - 160 (1989)
In an extract obtained from neutralized apple juice, cv.Jonathan, by LC separation on Amberlite XAD resin using ethyl acetate elution , 3-hydroxyoctyl β-D-glucoside was identified by HRGC, HRGC-MS and HRGC-FTIR after per-O-methylation.Chiral evaluation of free and glucosidically bound octane-1,3-diol was performed by HRGC after derivatization with Mosher's reagent revealing the occurrence of optically pure diol in apple fruit.By means of comparison of optical rotation of the 1,3-diacetoxy derivative with previously published data, (R)-(+)-configuration was evaluated.Key Word Index - Malus sylvestris; Rosaceae; apple; fruit; 3-hydroxyoctyl β-D-glucoside; free and bound (R)-(+)-octane-1,3-diol.
Regio-selective hydroxylation of gem-difluorinated octanes by alkane hydroxylase (AlkB)
Ramu, Ravirala,Chang, Chun-Wei,Chou, Ho-Husan,Wu, Li-Lan,Chiang, Chih-Hsiang,Yu, Steve S.-F.
supporting information; experimental part, p. 2950 - 2953 (2011/06/23)
gem-Difluoromethylene substituted molecules constitute a distinct class of fluorinated compounds. In this study, special chemistry has been developed for their preparation based on the highly selective terminal hydroxylation of these gem-difluorinated oct
Extracts of Isochrysis sp.
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, (2010/04/25)
The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.
Extracts of isochrysis sp.
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, (2010/04/25)
The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.
EXTRACTS OF TETRASELMIS SP.
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, (2010/06/19)
The present invention relates to extracts of Tetraselmis sp., preferably Tetraselmis suecica, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Tetraselmis sp., preferably Tetraselmis suecica.
Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes
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, (2010/06/20)
The present invention relates to extracts of Tetraselmis sp., preferably Tetraselmis suecica, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Tetraselmis sp., preferably Tetraselmis suecica.
Synthese de l'acide (dimercapto-1,3 propyl-2)-15 pentadecanoique, complexant potentiel du 99mTc
Alagui, Abdelhakim,Apparu, Marcel,Comet, Michel,Pasqualini, Roberto,Vidal, Michel
, p. 113 - 117 (2007/10/02)
The synthesis of 15-(1,3-dimercapto 2-propyl) pentadecanoic acid was performed in ten steps.One of these steps is the condensation of (5) with 7-bromoheptanoic acid.It is achieved in liquid ammonia or in a HMPA-THF medium with yields higher than 50 percent.In the second case a-5 bromoacid-ratio of 2.1 (slightly superior to the stoichiometry) is sufficient to obtain these yields, whereas in ammonia, the ratio must be higher than 5 and is therefore clearly unfavourable.The reaction times are also much longer in ammonia.The obtention of 5 from diethyl (6-bromohexyl) malonate 2 implies the reduction of ester functions and the substitution of Br by the ethynyl group.The optimal conditions and the sequence of these two steps have been determined.
Interphenylene carbacyclin derivatives
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, (2008/06/13)
A compound of the formula STR1 and intermediates useful in preparing same.
