13117-35-6

Basic information

• Product Name: 3-[3-(Dimethylamino)propyl]-1H-indole
• Synonyms: N,N-Dimethyl-1H-indole-3-propan-1-amine;Nsc88622;N,N-DIMETHYLHOMOTRYPTAMINE;3-[3-(Dimethylamino)propyl]-1H-indole
• CAS NO: 13117-35-6
• Molecular Formula: C13H18 N2
• Molecular Weight: 202.2954
• Mol File: 13117-35-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 344.8°Cat760mmHg
• Flash Point: 162.3°C
• Appearance: /
• Density: 1.056g/cm³
• Vapor Pressure: 6.45E-05mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 3-[3-(Dimethylamino)propyl]-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(Dimethylamino)propyl]-1H-indole(13117-35-6)
• EPA Substance Registry System: 3-[3-(Dimethylamino)propyl]-1H-indole(13117-35-6)

Safety Data

• Hazardous Substances Data: 13117-35-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18N2/c1-15(2)9-5-6-11-10-14-13-8-4-3-7-12(11)13/h3-4,7-8,10,14H,5-6,9H2,1-2H3

Upstream product

• 25109-08-4 toluene-4-sulfonic acid 3-(1H-indol-3-yl)propyl ester 
• 506-59-2 N,N-dimethylammonium chloride 
• 110-87-2 3,4-dihydro-2H-pyran 
• 3569-21-9 1H-indole-3-propanol 
• 100-63-0 phenylhydrazine 
• 830-96-6 Indole-3-propionic acid 
• 120-72-9 indole 
• 124-40-3 dimethyl amine 
• 360788-02-9 3-(1H-indol-3-yl)propionaldehyde 
• 31771-46-7 3-(1H-indol-3-yl)-N,N-dimethylpropanamide 

Relevant articles and documents

Indole derivatives and its application on the medicament

The invention provides indole derivatives or stereisomers, tautomers, nitrogen oxides, solvate, metabolic products, pharmaceutically acceptable salts or prodrugs thereof for treating the alzheimer disease. The invention further discloses a pharmaceutical composition containing the compounds and a method of using the compounds or the pharmaceutical composition thereof to treat the alzheimer disease.

Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)

A series of N,N-dimethylhomotryptamines was prepared and their binding affinities at the serotonin transporter (SERT) were determined. Compounds possessing an electron withdrawing substituent at the C5-position of the indole nucleus were found to be poten

Design and synthesis of aminopropyl tetrahydroindole-based indolin-2-ones as selective and potent inhibitors of Src and Yes tyrosine kinase

A novel series of substituted 3-[3-(aminopropyl)-4,5,6,7-tetrahydro-1H- indol-2-ylmethylene]-1,3-dihydro-indole-2-ones was discovered as potent inhibitors of the non-receptor tyrosine kinase Src and Yes. A structure-activity relationship was developed in order to optimize their potency and selectivity. Syntheses of these compounds are also described herein.