131189-26-9Relevant articles and documents
SYNTHESIS, CRYSTAL STRUCTURE, AND DFT STUDIES OF ETHYL 4-HYDROXY-2-(4-METHOXYPHENYL)-5-OXO- 1-PHENYL-2,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLATE
Ahankar,Ramazani,Saeidian,?lepokura,Lis
, p. 47 - 57 (2021/02/26)
Abstract: An efficient method for the synthesis of a new highly substituted pyrrolidinone derivative is developed via a three-component one-pot reaction of aniline, diethyl acetylenedicarboxylate, and 4-anisaldehyde. The structure of ethyl 4-hydroxy-2-(4-methoxyphenyl)-5-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carboxylate is confirmed by FTIR, 1H and 13C NMR spectroscopy. Unambiguous evidence for the structure of the synthesized product is obtained from the single crystal X-ray analysis. The comparison of both its molecular structure and intermolecular interactions with the previously known analogous compounds reveals that the mutual syn- or antiperiplanar orientation of ester C=O and pyrrolinone-bound OH is related to the type of molecular dimers formed in the solid state. The geometrical structure, the HOMO–LUMO analysis (electrophilicity index), 1H and 13C chemical shifts of the desired product are also calculated by DFT at the B3LYP level with the 6-31++G(d,p) basis set. The calculated chemical shifts are in compliance with the experimental data.
Synthesis of Ethyl 3-Methyl-4,5-dioxo-1,2-diphenylpyrrolidine-3-carboxylate Analogues Using Green and Expeditious Grinding Method
Hamzah, A. S.,Johari, S. A.,Mohammat, M. F.,Rashid, F. N. A. Abdul,Safyudin, U.,Salleh, S. N. Md.,Shaameri, Z.
, p. 2272 - 2279 (2021/12/23)
Abstract: A specific efficient method of synthesis of biologically active analogues of the title compound from acetylene dicarboxylate, aniline and various aromatic aldehydes catalyzed by citric acid by one-pot mortar-pestle grinding is described. The sho
Magnetic cobalt ferrite nanoparticles functionalized with citric acid as a green nanocatalyst for one-pot three-component sonochemical synthesis of substituted 3-pyrrolin-2-ones
Ahankar, Hamideh,Ramazani, Ali,?lepokura, Katarzyna,Lis, Tadeusz,Kinzhybalo, Vasyl
, p. 5007 - 5025 (2019/07/03)
Abstract: A clean, convenient and facile approach for one-pot ultrasonic assisted synthesis of substituted 3-pyrrolin-2-ones from diethyl acetylenedicarboxylate, aniline and aldehyde derivatives is described. The reactions were carried out in the presence
