1312290-82-6

Basic information

• Product Name: {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol
• Synonyms: {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol
• CAS NO: 1312290-82-6
• Molecular Weight: 382.893
• Mol File: 1312290-82-6.mol

Chemical Properties

• CAS DataBase Reference: {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol(CAS DataBase Reference)
• NIST Chemistry Reference: {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol(1312290-82-6)
• EPA Substance Registry System: {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol(1312290-82-6)

Safety Data

• Hazardous Substances Data: 1312290-82-6(Hazardous Substances Data)

Upstream product

• 802541-81-7 (5-amino-2-(4-methylpiperazin-1-yl)phenyl)methanol 
• 86-98-6 4,7-dichloroquinoline 
• 802541-80-6 [2-(4-methylpiperazin-1-yl)-5-nitrophenyl]methanol 
• 63878-73-9 (2-fluoro-5-nitrophenyl)methanol 
• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 109-01-3 1-methyl-piperazine 

Downstream Products

• 1071217-87-2 7-chloro-N-[4-(4-methylpiperazino)-3-(pyrrolidinomethyl)phenyl]quinolin-4-amine 
• 1312290-78-0 N-{3-[(tert-butylamino)methyl]-4-(4-methylpiperazino)phenyl}-7-chloroquinolin-4-amine 
• 1312290-81-5 7-chloro-N-[4-(4-methylpiperazino)-3-(morpholinomethyl)phenyl]quinolin-4-amine 
• 1312290-83-7 7-chloro-N-[3-({[2-(dimethylamino)ethyl](methyl)amino}methyl)-4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-amine 

Relevant articles and documents

7-CHLORO-QUINOLIN-4-AMINE COMPOUNDS AND USES THEREOF FOR THE PREVENTION OR TREATMENT OF DISEASES INVOLVING FORMATION OF AMYLOID PLAQUES AND/OR WHERE A DYSFUNCTION OF THE APP METABOLISM OCCURS

The present invention relates to compounds having the following Formula (I) for use in the prevention and/or the treatment of diseases involving formation of amyloid plaques and/or where a dysfunction of the APP metabolism occurs.

Optimized and convergent synthesis of potent anti-malarial aminoquinoline compounds: Easy access to analogs

Amodiaquine is one of the most active antimalarial 4-aminoquinoline. Previously we have described new analogs of amodiaquine and amopyroquine, in which the hydroxyl group was replaced by various amino groups and identified highly potent compounds. Here we