802541-81-7

Basic information

• Product Name: Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)- (9CI)
• Synonyms: Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)- (9CI)
• CAS NO: 802541-81-7
• Molecular Formula: C₁₂H₁₉N₃O
• Molecular Weight: 221.29876
• Product Categories: METHYL
• Mol File: 802541-81-7.mol

Chemical Properties

• Melting Point: 162～164℃
• Appearance: /
• CAS DataBase Reference: Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)- (9CI)(802541-81-7)
• EPA Substance Registry System: Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)- (9CI)(802541-81-7)

Safety Data

• Hazardous Substances Data: 802541-81-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)(9CI) is utilized as a key intermediate in the synthesis of novel drugs and pharmaceuticals. Its complex structure and multiple functional groups allow for a broad range of biological activities and interactions, making it a valuable asset in drug discovery and development processes.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)(9CI) serves as a versatile building block for the creation of new compounds with potential therapeutic applications. Its ability to engage in various chemical reactions and form stable complexes with other molecules makes it an attractive candidate for the design of innovative pharmaceutical agents.
Used in the Study of Biological Processes and Pathways:
Due to its potential to exhibit a wide range of biological activities, Benzenemethanol, 5-amino-2-(4-methyl-1-piperazinyl)(9CI) is also employed in research aimed at understanding various biological processes and pathways. This can lead to the development of targeted therapies and a deeper comprehension of the molecular mechanisms underlying different diseases and conditions.

Upstream product

• 30742-63-3 2-(4-methylpiperazin-1-yl)-5-nitrobenzaldehyde 
• 2965-22-2 methyl 2-fluoro-5-nitro-benzoate 
• 7304-32-7 2-fluoro-5-nitrobenzoic acid 
• 735213-47-5 methyl 2-(4-methyl-piperazin-1-yl)-5-nitro-benzoate 
• 109-01-3 1-methyl-piperazine 
• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 63878-73-9 (2-fluoro-5-nitrophenyl)methanol 
• 802541-80-6 [2-(4-methylpiperazin-1-yl)-5-nitrophenyl]methanol 

Downstream Products

• 1312290-82-6 {5-[(7-chloroquinolin-4-yl)amino]-2-(4-methylpiperazino)phenyl}methanol 
• 1071217-87-2 7-chloro-N-[4-(4-methylpiperazino)-3-(pyrrolidinomethyl)phenyl]quinolin-4-amine 
• 1312290-78-0 N-{3-[(tert-butylamino)methyl]-4-(4-methylpiperazino)phenyl}-7-chloroquinolin-4-amine 
• 1312290-81-5 7-chloro-N-[4-(4-methylpiperazino)-3-(morpholinomethyl)phenyl]quinolin-4-amine 
• 1312290-83-7 7-chloro-N-[3-({[2-(dimethylamino)ethyl](methyl)amino}methyl)-4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-amine 

Relevant articles and documents

MACROCYCLIC COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATIONS THEREOF

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The present invention relates to a macrocyclic derivative of pyrazole[3,4-d]pyrimidin-3-one as shown in the formula (I) and/or a pharmaceutically acceptable salt thereof, and a composition of a compound of the formula (I) and/or a pharmaceutically acceptable salt thereof, a preparation method thereof, application thereof as a Wee1 inhibitor and application thereof as a sensitizer for cancer chemotherapy or radiotherapy. The macrocyclic derivative of pyrazole[3,4-d]pyrimidin-3-one can effectively inhibit Wee1 and related signaling pathways, and has good cancer treatment and/or relieving effect.The formula is shown in the description.

7-CHLORO-QUINOLIN-4-AMINE COMPOUNDS AND USES THEREOF FOR THE PREVENTION OR TREATMENT OF DISEASES INVOLVING FORMATION OF AMYLOID PLAQUES AND/OR WHERE A DYSFUNCTION OF THE APP METABOLISM OCCURS

The present invention relates to compounds having the following Formula (I) for use in the prevention and/or the treatment of diseases involving formation of amyloid plaques and/or where a dysfunction of the APP metabolism occurs.

Optimized and convergent synthesis of potent anti-malarial aminoquinoline compounds: Easy access to analogs

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PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.