1312581-11-5

Basic information

• Product Name: 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 1312581-11-5
• Molecular Weight: 552.843
• Mol File: 1312581-11-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(1312581-11-5)
• EPA Substance Registry System: 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(1312581-11-5)

Safety Data

• Hazardous Substances Data: 1312581-11-5(Hazardous Substances Data)

Upstream product

• 1312581-05-7 4-chloro-2-iodo-1-methoxymethyl-1H-pyrrolo[2,3-b]pyridine 
• 1312581-04-6 4-chloro-1-(methoxymethyl)-1H-pyrrolo[2,3-b]pyridine 
• 1312581-10-4 4-[4-(4-chloro-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester 
• 1312581-09-1 4-chloro-2-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine 
• 940948-29-8 4-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine 
• 457613-78-4 4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylboronic acid 
• 55052-28-3 4-chloro-7-azaindole 

Downstream Products

• 1312579-40-0 3-[4-chloro-1-methyl-2-(4-piperazin-1-yl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-N-(2-dimethylamino-ethyl)-benzamide 

Relevant articles and documents

Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors – Part I

Novel N-substituted azaindoles have been discovered as PIM1 inhibitors. X-ray structures have played a significant role in orienting the chemistry effort in the initial phase of hit confirmation. Disclosure of an unconventional binding mode for 1 and 2, as demonstrated by X-ray crystallography, is presented and was an important factor in selecting and advancing a lead series.