940948-29-8

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-;4-Chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine;4-Chloro-2-iodo-7-azaindo...
• CAS NO: 940948-29-8
• Molecular Formula: C₇H₄ClIN₂
• Molecular Weight: 278.48
• Product Categories: Azaindoles
• Mol File: 940948-29-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 374 °C at 760 mmHg
• Flash Point: 180 °C
• Appearance: /
• Density: 2.156 g/cm³
• Vapor Pressure: 1.85E-05mmHg at 25°C
• Refractive Index: 1.784
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 11.54±0.40(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-(940948-29-8)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-(940948-29-8)

Safety Data

• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 940948-29-8(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo- is a chemical compound with the molecular formula C8H5ClIN. It is a heterocyclic compound that contains both chlorine and iodine atoms. 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo- can be used as a building block in the synthesis of various organic compounds and pharmaceuticals. It is also a useful reagent in chemical research and organic synthesis, particularly in the development of new drugs and agrochemicals. The presence of both chlorine and iodine in its structure gives it unique reactivity, making it an important intermediate in the production of diverse chemical compounds.

InChI:InChI=1/C7H4ClIN2/c8-5-1-2-10-7-4(5)3-6(9)11-7/h1-3H,(H,10,11)

Upstream product

• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 
• 271-63-6 7-Azaindole 
• 1312581-05-7 4-chloro-2-iodo-1-methoxymethyl-1H-pyrrolo[2,3-b]pyridine 
• 1312581-04-6 4-chloro-1-(methoxymethyl)-1H-pyrrolo[2,3-b]pyridine 
• 55052-28-3 4-chloro-7-azaindole 
• 940948-31-2 4-chloro-2-iodo-1-(2-iodobenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1312581-09-1 4-chloro-2-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine 
• 1312581-10-4 4-[4-(4-chloro-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester 
• 1312579-40-0 3-[4-chloro-1-methyl-2-(4-piperazin-1-yl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-N-(2-dimethylamino-ethyl)-benzamide 
• 1312581-11-5 4-[4-(4-chloro-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES

The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases

AZAINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

The disclosure relates generally to compounds that inhibit Pim kinases. Provided herein are N-substituted azaindoles, or pharmaceutically acceptable salts thereof, which are useful as selective inhibitors of Pim kinases. The disclosure also relates to pharmaceutical compositions comprising these compounds, processes for their preparation, and methods of using the same.