13141-48-5

Basic information

• Product Name: 2-CYCLOHEXYL-1H-INDOLE
• Synonyms: 2-CYCLOHEXYL-1H-INDOLE
• CAS NO: 13141-48-5
• Molecular Formula: C₁₄H₁₇N
• Molecular Weight: 199.29
• Mol File: 13141-48-5.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CYCLOHEXYL-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOHEXYL-1H-INDOLE(13141-48-5)
• EPA Substance Registry System: 2-CYCLOHEXYL-1H-INDOLE(13141-48-5)

Safety Data

• Hazardous Substances Data: 13141-48-5(Hazardous Substances Data)

Usage

General Description

2-Cyclohexyl-1H-indole is a chemical compound with an indole core structure, which is a ubiquitous framework found in a variety of natural products, pharmaceuticals, and agrochemicals. It is characterized by the presence of cyclohexyl, a saturated alicyclic hydrocarbon compound, linked to an indole moiety. Indoles are significant in biological systems, for instance, the amino acid tryptophan is an indole derivative. The properties and uses of 2-cyclohexyl-1H-indole can vary widely depending on the presence of other functional groups and substitution patterns on the molecule. As with any compound, the handling and potential effects of 2-cyclohexyl-1H-indole should be guided by appropriate safety data.

Upstream product

• 615-43-0 2-iodophenylamine 
• 823-76-7 Cyclohexyl methyl ketone 
• 26686-10-2 4,7-dihydro-1H-indole 
• 108-94-1 cyclohexanone 
• 695-12-5 vinylcyclohexane 
• 615-36-1 2-bromoaniline 
• 120-72-9 indole 
• 110-82-7 cyclohexane 
• 931-48-6 2-cyclohexylacetylene 
• 2727-71-1 N-(2-bromophenyl)-2,2,2-trifluoroacetamide 
• 108-90-7 chlorobenzene 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 95-53-4 o-toluidine 
• 153407-55-7 N-(o-tolyl)cyclohexanecarboxamide 

Downstream Products

• 899419-79-5 tert-butyl 2-cyclohexyl-1H-indole-1-carboxylate 
• 1416576-67-4 C₂₃H₂₇NO₃S 
• 1416576-68-5 C₂₄H₂₇NO₄ 
• 68051-20-7 2-cyclohexyl-1-methyl-1H-indole 
• 26216-92-2 2-cyclohexanylindoline 
• 1397585-87-3 (E)-2-cyclohexyl-3-styryl-1H-indole 
• 938326-31-9 2-cyclohexyl-1H-indole-3-carbonitrile 
• 1234333-44-8 (+)-(S)-2-cyclohexanylindoline 
• 1374408-58-8 (R)-2-cyclohexanylindoline 
• 84543-25-9 ethyl 2-azido-3-(2-cyclohexyl-1-methoxymethylindol-3-yl)propenoate 
• 84543-31-7 ethyl 2-amino-3-(2-cyclohex-1-enyl-1-methoxymethylindol-3-yl)propenoate 
• 84543-21-5 2-cyclohexyl-1-methoxymethylindole-3-carbaldehyde 

Relevant articles and documents

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A facile one-pot method to synthesise 2-alkylated indole and 2,2′-bis(indolyl)methane derivatives using ketones as electrophiles and their anion sensing ability

Indole derivatives are of great importance because of their biological activity and application in technology. This study explores the synthesis of 2-alkylated indoles derivatives and 2,2′-bis(indolyl)methanes, and their application in anion sensing. The synthesis of a wide range of 2-alkylated indoles and some 2,2′-bis(indolyl)methanes, which cannot be synthesized by previously reported methods, was for the first time accomplished employing dipole exchange of the indole ring towards electrophilic substitution. Some of the indole derivatives exhibited selective recognition and sensing ability towards F- and HSO4- anions through naked-eye detectable color changes. The sensing details of the indole derivatives were also evaluated using UV-Vis spectroscopy and 1H NMR titration techniques.

Phosphine ligand 2 - alkyl - indole skeleton as well as preparation method and application thereof

The invention discloses a phosphine ligand 2 - alkyl - indole skeleton and a preparation method and application thereof, wherein the structural formula of the phosphine ligand 2 - alkyl - indole skeleton is shown I. , Wherein R. 1 . R2/su

A Divergent Approach to Indoles and Oxazoles from Enamides by Directing-Group-Controlled Cu-Catalyzed Intramolecular C-H Amination and Alkoxylation

A directing-group-controlled, copper-catalyzed divergent approach to indoles and oxazoles from enamides has been developed. The picolinamide-derived enamides undergo the intramolecular aromatic C-H amination in the presence of a Cu(OPiv)2 catalyst and an MnO2 oxidant to form the corresponding indoles in good yields. On the other hand, simpler aryl- or alkyl-substituted enamides are converted to the 2,4,5-trisubstituted oxazole frameworks via vinylic C-H alkoxylation under identical conditions. The copper catalysis can provide uniquely divergent access to indole and oxazole heteroaromatic cores of great importance in medicinal and material chemistry.