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CAS

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131427-22-0

1-Benzyl-3-(chloroMethyl)-1H-indazole, commonly known as CUMYL-CHLORO, is a synthetic cannabinoid that functions as a potent agonist at the CB1 and CB2 receptors. It is a psychoactive substance with a range of adverse effects, leading to its ban in several countries. CUMYL-CHLORO is typically marketed as a research chemical or designer drug, utilized for its psychoactive effects such as euphoria, relaxation, and altered perception.

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  • 131427-22-0 Structure

  • Basic information

    1. Product Name: 1-Benzyl-3-(chloroMethyl)-1H-indazole
    2. Synonyms: 1-Benzyl-3-(chloroMethyl)-1H-indazole;1-Benzyl-3-(chloromethyl)
    3. CAS NO:131427-22-0
    4. Molecular Formula: C15H13ClN2
    5. Molecular Weight: 256.73012
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 131427-22-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 431.2±33.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.20±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 0.77±0.50(Predicted)
    10. CAS DataBase Reference: 1-Benzyl-3-(chloroMethyl)-1H-indazole(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-Benzyl-3-(chloroMethyl)-1H-indazole(131427-22-0)
    12. EPA Substance Registry System: 1-Benzyl-3-(chloroMethyl)-1H-indazole(131427-22-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 131427-22-0(Hazardous Substances Data)

131427-22-0 Usage

Uses

Used in Research Applications:
1-Benzyl-3-(chloroMethyl)-1H-indazole is used as a research chemical for studying the effects and mechanisms of action at the CB1 and CB2 receptors. It aids in understanding the role of these receptors in various physiological and pathological processes, potentially leading to the development of new therapeutic agents.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-Benzyl-3-(chloroMethyl)-1H-indazole is used as a lead compound in the development of new drugs targeting the CB1 and CB2 receptors. Its potent agonist activity can be leveraged to create medications for conditions such as pain management, inflammation, and neurodegenerative disorders.
Used in Forensic Toxicology:
1-Benzyl-3-(chloroMethyl)-1H-indazole is utilized in forensic toxicology as a reference substance for the identification and analysis of synthetic cannabinoids in biological samples. This helps in the detection and monitoring of the use of designer drugs and their potential involvement in cases of drug abuse or intoxication.

Check Digit Verification of cas no

The CAS Registry Mumber 131427-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,4,2 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 131427-22:
(8*1)+(7*3)+(6*1)+(5*4)+(4*2)+(3*7)+(2*2)+(1*2)=90
90 % 10 = 0
So 131427-22-0 is a valid CAS Registry Number.

131427-22-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-?Indazole, 3-?(chloromethyl)?-?1-?(phenylmethyl)?-

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131427-22-0 SDS

131427-22-0Downstream Products

131427-22-0Relevant articles and documents

PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL- 1H- INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES

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, (2011/02/24)

The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (I).

PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDR0XYMETHYL-1H-INDAZ0LE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES

-

, (2011/02/24)

The present invention relates to the process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to be used in a subsequent process for the preparation of 1-benzyl-3- hydroxymethyl-1H-indazole according to formula (I).

Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids

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, (2008/06/13)

Compounds of the formula, A-CH2-O-CRR?-COOR''' (I), wherein A, R, R? and R''' have the meanings mentioned in the description, salts thereof with pharmaceutically acceptable bases, intermediates and processes for their preparation, and pharmaceutical compositions containing them.

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