13143-28-7Relevant academic research and scientific papers
Pd-Catalyzed Ortho-Directed C—H Glycosylation of Arenes Using N-linked Bidentate Auxiliaries
Wang, Quanquan,Zhu, Wanjun,Sun, Qikai,He, Gang,Chen, Gong
supporting information, p. 571 - 576 (2021/02/01)
A set of Pd-catalyzed ortho-directed C—H glycosylation reactions with glycosyl chloride donors using various N-linked bidentate auxiliaries has been developed for synthesis of C-aryl glycosides. A broad range of pyranose and furanose moieties can be installed on the ortho position of arylamine, carbazole, indole and benzylamine type substrates in high yield and with high regio- and diastereoselectivity. These auxiliaries can be readily installed and removed under relatively mild conditions.
Photocatalyzed synthesis of unsymmetrical ureas via the oxidative decarboxylation of oxamic acids with PANI-g-C3N4-TiO2 composite under visible light
Wang, Liang,Wang, Hao,Wang, Yaoyao,Shen, Minggui,Li, Shubai
supporting information, (2020/04/28)
The synthesis of unsymmetrical ureas via the photocatalyzed oxidative decarboxylation of oxamic acids has been developed. The carbamoyl radicals were generated from oxamic acids in the presence of a hypervalent iodine reagent and the PANI(Polyaniline)-g-C3N4-TiO2 composite under visible light irradiation. The radicals were converted in situ into the corresponding isocyanates, which were then trapped by amines to afford the corresponding products in moderate to good yields. This protocol avoided the direct use of environmentally unfriendly isocyanates and a series of substrates were tolerated. Moreover, the photocatalyst could be readily recovered by simple filtration and be reused for several runs with only a slight decrease in the catalytic activity.
Pd/C-Catalyzed Domino Synthesis of Urea Derivatives Using Chloroform as the Carbon Monoxide Source in Water
Wang, Liang,Wang, Hao,Li, Guiqing,Min, Shuliang,Xiang, Fangyuan,Liu, Shiqi,Zheng, Waigang
, p. 4585 - 4593 (2018/10/31)
A Pd/C-catalyzed domino synthesis of symmetrical and unsymmetrical ureas from aryl iodides, sodium azide, amines and CHCl3 in water has been developed. This reaction proceeds with sequential carbonylation, Curtius rearrangement and nucleophilic addition. CHCl3 serves as a convenient and safe alternation of CO gas in the presence of KOH. A series of urea derivatives were obtained in moderate to good yields with good functional group tolerance. Furthermore, the Pd/C catalyst could be readily recovered with slight decrease in the catalytic activity after six consecutive runs. (Figure presented.).
An efficient transformation of ethers to N,N′-disubstituted ureas in a Ritter type reaction
Panduranga, Veladi,Basavaprabhu,Sureshbabu, Vommina V.
, p. 975 - 979 (2013/04/10)
A simple, mild, and an alternative protocol for the preparation of N,N′-disubstituted ureas from readily available ethers and cyanamides as starting materials is described. The protocol explores the reactivity of ether in a Ritter type reaction with cyanamide in the presence of BF 3·Et2O and resulting in the formation of N,N′-disubstituted urea. Divinyl ether as well as MTBE (methyl tert-butyl ether) can be employed as ether components to afford allyl and tert-butyl ureas respectively.
Ion-exchange resins for solution phase parallel synthesis of chemical libraries
Gayo, Leah M.,Suto, Mark J.
, p. 513 - 516 (2007/10/03)
Described are various techniques that employ ion-exchange resins for the solution-phase synthesis of chemical libraries. We have found these resins to be useful as reagents and/or scavengers in a variety of reactions. Nine basic ion-exchange resins were e
