131550-34-0

Upstream product

• 141364-53-6 N'-[(S)-2-Cyclohexyl-1-((4R,5S)-5-isobutyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-N,N-dimethyl-hydrazine 
• 85254-46-2 2,3-(isopropylidenedioxy)-4,4-dihydroxybutanic acid lactone 
• 141364-54-7 (4S,5R)-2,2-Dimethyl-4-(2-methylpropan-1-yl)-5-(hydroxymethyl)-1,3-dioxolane 
• 139727-13-2 (4S,5R)-2,2-Dimethyl-4-(2-methyl-1-propenyl)-5-(hydroxymethyl)-1,3-dioxolane 
• 117161-13-4 (4S,5R)-4-cyclohexylmethyl-5-<(1'S)-1'-hydroxy-3-methylbutyl>oxazolidin-2-one 
• 139727-18-7 (4S,5S)-5-Isobutyl-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 139727-17-6 (4S,5R)-2,2-Dimethyl-4-(2-methylpropan-1-yl)-5-vinyl-1,3-dioxolane 
• 147879-36-5 (3R,4S)-3,4-Dihydroxy-6-methylhept-1-ene 
• 189996-60-9 2,3-O-isopropylidene-D-erythrose 
• 122621-77-6 (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 77-76-9 2,2-dimethoxy-propane 
• 141364-52-5 (4S,5S)-2,2-Dimethyl-4-(2-methylpropyl)-5-formyl-1,3-dioxolane dimethyl hydrazone 
• 147879-38-7 methyl (2S,3S)-2,3-dihydroxy-5-methyl-4-hexenoate acetonide 
• 147879-37-6 (2S,3S)-2,3-dihydroxy-5-methyl-4-hexenoic acid acetonide 

Downstream Products

• 136010-42-9 N-(tert-butoxycarbonyl)-4-thiazolylalaninyl amide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 104882-10-2 (2S,3R,4S)-2-[(tert-butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 104882-45-3 (S)-2-amino-1-cyclohexyl-(R)-3,(S)-4-dihydroxy-6-methylheptane hydrochloride 
• 143285-53-4 (4S,5R)-2,2-dimethyl-4-(2-methylpropan-1-yl)-5-<(1S)-1--2-cyclohexylethyl>-1,3-dioxolane 

Relevant academic research and scientific papers

Dipeptide Isosteres. 1. Synthesis of Dihydroxyethylene Dipeptide Isosteres via Diastereoselective Additions of Alkyllithium Reagents to N,N-Dimethylhydrazones. Preparation of Renin and HIV-1 Protease Inhibitor Transition-State Mimics

The amino and diamino dihydroxyethylene dipeptide isosteres 19a,b and 23 are important intermediates for the preparation of inhibitors of human renin and HIV-1 protease, respectively.A general synthetic strategy was developed to access both dipeptide isos

A practical synthesis of the dihydroxyethylene dipeptide isostere, (2S, 3R, 4S) 2-[(tert-butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, from D-isoascorbic acid

The N-Boc dihydroxyethylene dipeptide isostere 7 and its N-Boc 3-(thiazol-4-yl)alanyl derivative 8 were synthesized, without purification of intermediates, from (4S,5R)-2,2-dimethyl-4-(2-methylpropyl)-5-hydroxymethyl-1,3-dioxolane (3b), in 24 and 32% over

A Versatile, Efficient Synthesis of (-)-(2S, 3R, 4S)-2-Amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, The Abbott Pseudodipeptidyl Insert

An economic construction (6 steps, 36percent yield) of a valuable peptide analog subunit, the Abbott pseudodipeptidyl insert (-)-(2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane (1), has been developed.