1316848-30-2

Upstream product

• 109579-09-1 (5S)-5-benzyl-4-hydroxy-1-t-butoxycarbonylpyrrol-2(5H)-one 
• 2748-02-9 L-leucine tert-butyl ester hydrochloride 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 21691-53-2 L-leucine tert-butyl ester 
• 1316848-29-9 (5S)-1-((3S)-1-(2-benzyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl)pyrrolidin-3-yl)-4-(tert-butoxy)-5-isobutyl-1H-pyrrol-2(5H)-one 
• 1316848-06-2 C₂₂H₃₄N₂O₄*ClH 
• 1316848-05-1 C₂₂H₃₄N₂O₄ 
• 69358-30-1 (5S)-5-benzylpyrrolidine-2,4-dione 
• 1316848-18-6 (S)-4-(tert-butoxy)-5-isobutyl-1-((S)-pyrrolidin-3-yl)-1H-pyrrol-2(5H)-one 

Relevant academic research and scientific papers

Pyrrolinone-pyrrolidine oligomers as universal peptidomimetics

Peptidomimetics 1-3 were prepared from amino acid-derived tetramic acids 7 as the key starting materials. Calculations show that preferred conformations of 1 can align their side-chain vectors with amino acids in common secondary structures more effectively than conformations of 3. A good fit was found for a preferred conformation of 2 (an extended derivative of 1) with a sheet/β-turn/sheet motif.