865156-50-9

Basic information

• Product Name: C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE
• Synonyms: C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE;C-(4-BROMO-PYRIDIN-2-YL)-METHAMINE;2-AMinoMethyl-4-broMopyri...;2-AMinoMethyl-4-broMopyridine;4-Bromo-2-pyridinemethanamine;1-(4-Bromo-2-pyridinyl)methanamine;(4-Bromo-2-pyridyl)methanamine;(4-BROMOPYRIDIN-2-YL)METHANAMINE Hbr
• CAS NO: 865156-50-9
• Molecular Formula: C₆H₇BrN₂
• Molecular Weight: 187.03718
• EINECS: 1806241-263-5
• Mol File: 865156-50-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 262.846 °C at 760 mmHg
• Flash Point: 112.766 °C
• Appearance: /
• Density: 1.574 g/cm³
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 8.42±0.39(Predicted)
• CAS DataBase Reference: C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE(865156-50-9)
• EPA Substance Registry System: C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE(865156-50-9)

Safety Data

• Hazardous Substances Data: 865156-50-9(Hazardous Substances Data)

Usage

General Description

C-(4-Bromo-pyridin-2-yl)-methylamine is a chemical compound with the molecular formula C6H7BrN2. It is a derivative of pyridine, and its structure includes a bromine atom attached to the 4-position of the pyridine ring, as well as a methylamine group attached to the pyridine ring. C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its properties and reactivity make it a useful building block for the production of various organic compounds. Additionally, it has potential applications in the field of medicinal chemistry and drug development. Safety data on this compound should be carefully reviewed and appropriate precautions should be taken when handling and using it.

InChI:InChI=1/C6H7BrN2/c7-5-1-2-9-6(3-5)4-8/h1-3H,4,8H2

Upstream product

• 1190108-35-0 4-bromo-2-(bromomethyl)pyridine hydrobromide 
• 131747-63-2 4-bromo-2-pyridinecarboxaldehyde 
• 131747-45-0 4-bromo-2-(hydroxymethyl)pyridine 
• 100367-74-6 4-bromo-2-methylpyridine N-oxide 
• 22282-99-1 4-bromo-2-methylpyridine 
• 62150-45-2 4-bromo-2-cyanopyridine 

Relevant articles and documents

Heterocyclic kinase inhibitor

The invention belongs to the technical field of medicines, and particularly relates to a heterocyclic DNA-PK kinase inhibitor compound shown as a general formula (I), a pharmaceutically acceptable salt and an isomer thereof, a pharmaceutical composition and preparation containing the compound, the pharmaceutically acceptable salt and the isomer thereof, a method for preparing the compound, the pharmaceutically acceptable salt and the isomer thereof, and application of the compound, the pharmaceutically acceptable salt and the isomer thereof.

BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I), or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3a, R3b and R4 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Human carbonic anhydrase II as host protein for the creation of artificial metalloenzymes: The asymmetric transfer hydrogenation of imines

In the presence of human carbonic anhydrase II, aryl-sulfonamide-bearing IrCp* pianostool complexes catalyze the asymmetric transfer hydrogenation of imines. Critical cofactor-protein interactions revealed by the X-ray structure of [(η5-Cp*)Ir(pico 4)Cl] 9 WT hCA II were genetically optimized to improve the catalytic performance of the artificial metalloenzyme (68% ee, kcat/KM 6.11 × 10 -3 min-1 mM-1).