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2-(4-bromophenylamino)acetic acid methyl ester is a chemical compound with the molecular formula C9H10BrNO2. It is a methyl ester derivative of 2-(4-bromophenylamino)acetic acid, containing a bromine atom and an amino group attached to a phenyl ring. 2-(4-bromophenylamino)acetic acid methyl ester is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds, including pharmaceutical drugs. It has potential applications in the development of new drugs for the treatment of various diseases and disorders.

131770-56-4

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131770-56-4 Usage

Uses

Used in Organic Synthesis:
2-(4-bromophenylamino)acetic acid methyl ester is used as a building block for the synthesis of various biologically active compounds. Its unique structure allows for the creation of a wide range of molecules with potential applications in various fields.
Used in Pharmaceutical Research:
2-(4-bromophenylamino)acetic acid methyl ester is used as a key intermediate in the development of new drugs. Its presence in the molecular structure can contribute to the desired pharmacological properties, making it a valuable component in the design and synthesis of novel therapeutic agents.
Used in Drug Development:
2-(4-bromophenylamino)acetic acid methyl ester is used as a starting material for the creation of new drug candidates. Its potential applications in the treatment of various diseases and disorders make it an important compound in the pharmaceutical industry.
It is important to handle 2-(4-bromophenylamino)acetic acid methyl ester with care, as it may have hazardous properties and should only be used by trained professionals in a controlled laboratory environment.

Check Digit Verification of cas no

The CAS Registry Mumber 131770-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,7 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 131770-56:
(8*1)+(7*3)+(6*1)+(5*7)+(4*7)+(3*0)+(2*5)+(1*6)=114
114 % 10 = 4
So 131770-56-4 is a valid CAS Registry Number.

131770-56-4Relevant articles and documents

Acid-catalyzed chemodivergent reactions of 2,2-dimethoxyacetaldehyde and anilines

Guo, Luxia,Chen, Zihao,Zhu, Hongmei,Li, Minghao,Gu, Yanlong

, p. 1419 - 1422 (2020/11/12)

Chemodivergent reactions of 2,2-dimethoxyacetaldehyde and anilines were described, which were established on the basis of either a C[sbnd]C bond cleavage or a rearrangement process of a reaction intermediate. These reactions proceeded in a condition-determined manner with good functional group tolerance. In the first model, 2,2-dimethoxyacetaldehyde reacted with aniline to form a new C[sbnd]N bond, in the presence of O2, via a C[sbnd]C bond cleavage reaction. However, in the second model, by performing the reaction in the absence of O2, Heyns rearrangement occurred and generated a new C[sbnd]O bond to form methyl phenylglycinate. Such condition-determined reactions not only offered the new way for value-added conversion of biomass-derived platform molecule, 2, 2-dimethoxyacetaldehyde, but also provided efficient methods for the synthesis of N-arylformamides and methyl phenylglycinates.

Transition-metal-free decarboxylation of dimethyl malonate: An efficient construction of α-amino acid esters using TBAI/TBHP

Zhang, Jie,Shao, Ying,Wang, Yaxiong,Li, Huihuang,Xu, Dongmei,Wan, Xiaobing

, p. 3982 - 3987 (2015/03/30)

A transition-metal-free decarboxylation coupling process for the preparation of α-amino acid esters, which succeeded in merging hydrolysis/decarboxylation/nucleophilic substitution, is well described. This strategy uses commercially available inexpensive starting materials, catalysts and oxidants and has a wide substrate scope and operational simplicity. This journal is

A new strategy for the construction of α-amino acid esters via decarboxylation

Zhang, Jie,Jiang, Jiewen,Li, Yuling,Zhao, Yun,Wan, Xiaobing

supporting information, p. 3222 - 3225 (2013/07/26)

A new α-amino acid esters formation reaction has been developed via decarboxylation. The methodology is distinguished by its practical novelty in terms of the readily accessible starting materials, environmentally benign reaction conditions and waste streams, and wide substrate scope.

ISOQUINOLINE-5-SULFONIC ACID AMIDES AS INHIBITORS OF AKT (PROTEIN KINASE B)

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Page 44, (2010/02/09)

The present invention relates to compounds Formula (I): as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.

5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B

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Page 62, (2010/02/07)

The invention concerns compounds of the formula (I) or pharmaceutically acceptable salts thereof (A chemical formula should be inserted here - please see paper copy enclosed herewith) wherein R1, R2, R3, R4, R5, and R6 have any of the meanings defined in the description. Processes for the manufacture of compounds of formula (I), compositions containing them, their use as inhibitors of protein tyrosine phosphatase PTP1B and their use for the treatment of diabetes mellitus are also described.

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