131853-35-5Relevant articles and documents
Nucleoside 3'-N,N-Dialkylphosphonamidates as Novel Nucleotide Units for the Solution-Phase Oligonucleotide Syntheis
Wada, Takeshi,Ishikawa, Kazushige,Hata, Tsujiaki
, p. 2043 - 2054 (1993)
Nucleoside 3'-N,N-diisopropylphosphonamidate building blocks for oligonucleotide syntheis were prepared in high yields from appropriately protected nucleosides by use of chlorobis(N,N-diisopropylamino)phosphine as a phosphitylating reagent.The 5'-dimethox
Nucleoside 3'-N,N-dialkylphosphonamidates: Novel building blocks for oligonucleotide synthesis
Wada,Ishikawa,Hata
, p. 6363 - 6366 (2007/10/02)
Nucleoside 3'-N,N-diisopropylphosphonamidates reacted with tris(2,4,6-tribromophenoxy)dichlorophosphorane (BDCP) to generate the corresponding aminophosphorochloridites without cleavage of the P-N bond. The reaction was applied to internucleotidic bond formation.