131896-42-9

Basic information

• Product Name: D-4-THIAZOLYLALANINE
• Synonyms: D-4-THIAZOLYLALANINE;H-D-ALA(4-THIAZOYL)-OH;H-D-ALA(4-THZ)-OH;3-(4-THIAZOLYL)-D-ALANINE;3-(4-THIAZOYL)-D-ALANINE;(R)-3-(4-THIAZOYL)-ALANINE;RARECHEM BK PT F200;D-3-(4-Thiazolyl)-alanine
• CAS NO: 131896-42-9
• Molecular Formula: C6H8N2O2S
• Molecular Weight: 172.2
• Product Categories: Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 131896-42-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 353.32 °C at 760 mmHg
• Flash Point: 167.482 °C
• Appearance: /
• Density: 1.433±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.64
• Storage Temp.: Store at -15°C
• PKA: 8.24±0.16(Predicted)
• CAS DataBase Reference: D-4-THIAZOLYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: D-4-THIAZOLYLALANINE(131896-42-9)
• EPA Substance Registry System: D-4-THIAZOLYLALANINE(131896-42-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 131896-42-9(Hazardous Substances Data)

Usage

Uses

D-4-Thiazolylalanine is a non-proteinogenic amino acid and can be used in studies requiring chiral non-proteinogenic amino acids.

InChI:InChI=1/C6H8N2O2S/c1-4(6(9)10)8-5-2-11-3-7-5/h2-4,8H,1H3,(H,9,10)/t4-/m0/s1

Upstream product

• 131116-54-6 diethyl (4-thiazolyl)methylacetamidomalonate 
• 134107-69-0 (R)-2-((tert-butoxycarbonyl)amino)-3-(thiazol-4-yl)propionic acid 
• 801240-92-6 (Z)-3-(4-thiazolyl)-2-benzoylaminoprop-2-enoic acid 
• 801240-93-7 (S)-3-(4-thiazolyl)-2-benzoylaminopropanoic acid 

Downstream Products

• 14598-91-5 2-benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 
• 119434-75-2 (S)-3-(4-thiazolyl)-2-tert-butoxycarbonylaminopropanoic acid 
• 14598-91-5 2-Benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 
• 204386-76-5 rovatirelin 
• 108868-73-1 ((S)-1-{1-[(1S,2S)-1-Cyclohexylmethyl-2-hydroxy-4-(4-methyl-pentanoylamino)-butylcarbamoyl]-2-thiazol-4-yl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 108868-87-7 Boc-Phe-dl-(4-thiazolyl)alanine methyl ester 
• 108868-88-8 Boc-Phe-dl-(4-thiazolyl)alanine 

Relevant articles and documents

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Substituted quinoxaline-2-ones as glutamate receptor antagonists

A novel series of substituted quinoxaline 2-ones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate receptor antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, seizure disorders, pain, Alzheimer's, Parkinson's, and Huntington's Diseases.

Studies of unnatural amino acids and their peptides. II. The syntheses of DL-beta-(4-thiazolyl)-alpha-alanine and its peptides.

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