132032-87-2

Upstream product

• 1191-16-8 3-methylbut-2-enyl acetate 
• 108-05-4 vinyl acetate 
• 53627-41-1 (E)-2-methyl but-2-ene-1,4-diol 

Downstream Products

• 26586-02-7 (E)-4-acetoxy-2-methylcrotonaldehyde 
• 928267-77-0 2-(4-bromo-2-methyl-but-2-enylamino)-benzoic acid methyl ester 
• 878143-08-9 methyl 2-(N-2-methyl-4-hydroxy-2-butenyl)amino benzoate 
• 878143-09-0 2-[5,5-bis-(diethoxy-phosphoryl)-2,8,12-trimethyl-trideca-2,7,11-trienylamino]-benzoic acid methyl ester 
• 928267-79-2 C₃₅H₅₂N₂O₁₀P₂ 
• 443892-56-6 (E)-4-hydroxy-3-methyl-2-butenyl pyrophosphate ammonium salt 
• 59055-00-4 2-methyl-2-butene-1,4-diyl (Z)-diacetate 
• 167687-19-6 (2E)-4-[(4-methoxyphenyl)methoxy]-2-methylbut-2-en-1-ol 
• 929897-51-8 (2E)-4-{[(tert-butyl)diphenylsilyl]oxy}-3-methylbut-2-en-1-ol 
• 68715-67-3 haagenolide 
• 61976-12-3 (E)-2-((4-bromo-3-methylbut-2-en-1-yl)oxy)tetrahydro-2H-pyran 
• 900149-88-4 ((2S,3S)-4-Methoxymethoxy-3-methyl-2,3-bis-triisopropylsilanyloxy-butoxymethyl)-benzene 

Relevant academic research and scientific papers

Highly regioselective lipase-catalyzed acetylation and hydrolysis of acyclic α,ω-terpenediols and their diacetates

Highly regioselective transformations of the acyclic α,ω-terpenediols and their diacetates to the monoacetates using lipase were accomplished. The acetylation of the α,ω-terpenediols gave regioselectively the ω-monoacetates 3, whereas the α-monoacetates 2 were obtained by hydrolysis of the α,ω-diacetates.

Synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids

The synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) was described by regioselective hydroxylation and diphosphorylation of dimethylallyl alcohol. The synthesis started from commercially available 3-methylbut-2-en-1-ol. The 1-alcohol function of starting material was converted to the acetate by treatment with pyridine acetic anhydride. Selective allylic hydroxylation was achieved using selenium dioxide and tert-butyl hydro-peroxide.