1323409-83-1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 874-89-5 4-Cyanobenzyl alcohol 
• 1323407-17-5 2-bromomethyl-3-(tert-butyl-dimethyl-silanyloxy)-benzoic acid methyl ester 
• 359629-73-5 3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-benzoic acid methyl ester 
• 603-80-5 3-hydroxy 2-methylbenzoic acid 
• 55289-05-9 methyl 3-hydroxy-2-methylbenzoate 

Downstream Products

• 1323404-94-9 3-(4-(4-((amino)methyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2.6-dione hydrochloride 

Relevant academic research and scientific papers

BIFUNCTIONAL COMPOUNDS AS CDK MODULATORS

The present application provides compounds of formulae I and II that modulate CDK protein function. Methods of making the compounds, compositions containing the compounds, and the compounds for use in a method of treating or ameliorating of diseases, disorders, or conditions associated with CDK proteins, are also disclosed.

ETHER COMPOUNDS AND USES THEREOF

The present invention provides compounds that modulate protein function, to restore protein homeostasis and/or cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions of these compounds are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions are also provided.