13286-62-9

Basic information

• Product Name: (+/-)-threo-3-Amino-1,2-diphenyl-propanol-⁽¹⁾
• CAS NO: 13286-62-9
• Molecular Weight: 227.306
• Mol File: 13286-62-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+/-)-threo-3-Amino-1,2-diphenyl-propanol-⁽¹⁾(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-threo-3-Amino-1,2-diphenyl-propanol-⁽¹⁾(13286-62-9)
• EPA Substance Registry System: (+/-)-threo-3-Amino-1,2-diphenyl-propanol-⁽¹⁾(13286-62-9)

Safety Data

• Hazardous Substances Data: 13286-62-9(Hazardous Substances Data)

Upstream product

• 5623-26-7 α-methylbenzoin 
• 63471-68-1 α-cyano-α'-hydroxy-bibenzyl 
• 108973-75-7 (+/-)-threo-3-Acetamino-1,2-diphenyl-propanol-⁽¹⁾ 
• 103385-06-4 3-Acetamino-1.2-diphenyl-propanon-⁽¹⁾ 
• 100-52-7 benzaldehyde 
• 140-29-4 phenylacetonitrile 
• 71312-66-8 3-hydroxy-2,3-diphenylpropionitrile 
• 108973-75-7 (+/-)-erythro-3-Acetamino-1,2-diphenyl-propanol-⁽¹⁾ 
• 134-81-6 benzil 
• 92435-53-5 3-chloro-1,2-diphenylpropan-1-one 
• 451-40-1 phenyl benzyl ketone 
• 743364-14-9 (+/-)-3-Amino-1.2-diphenyl-propanon-⁽¹⁾ 

Downstream Products

• 18456-33-2 (+/-)-threo-3-Dimethylamino-1,2-diphenyl-propanol-⁽¹⁾ 
• 114381-17-8 (+/-)-threo-3-Thiobenzamino-1,2-diphenyl-propanol-⁽¹⁾ 
• 114381-17-8 (+/-)-erythro-3-Thiobenzamino-1,2-diphenyl-propanol-⁽¹⁾ 
• 102313-61-1 (+/-)-erythro-N-<3-Hydroxy-2,3-diphenyl-propyl>-benzamidin 

Relevant articles and documents

Anti-Selective Aldol Reaction of Benzylic Nitriles and Synthesis of γ-Amino Alcohols

The stereochemistry of the aldol reaction of seven benzylic nitriles 1a-g and four aldehydes 2-5 has been studied.In all cases studied the reaction is anti-selective.Good to excellent selectivity (10:1 -> 20:1) can be obtained if aldehydes with bulky secondary or tertiary substituents are used.The resulting aldols 6-9 are easily transformed to the corresponding γ-amino alcohols 12-15, which may possess useful antidepressant activity.