132874-06-7

Basic information

• Product Name: methyl 3-(bromomethyl)-2-nitrobenzoate
• Synonyms: 3-Bromomethyl-2-nitro-benzoic acid methyl ester; Benzoic acid, 3-(bromomethyl)-2-nitro-, methyl ester
• CAS NO: 132874-06-7
• Molecular Formula: C₉H₈BrNO₄
• Molecular Weight: 274.07082
• Mol File: 132874-06-7.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: methyl 3-(bromomethyl)-2-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(bromomethyl)-2-nitrobenzoate(132874-06-7)
• EPA Substance Registry System: methyl 3-(bromomethyl)-2-nitrobenzoate(132874-06-7)

Safety Data

• Hazardous Substances Data: 132874-06-7(Hazardous Substances Data)

Usage

General Description

Methyl 3-(bromomethyl)-2-nitrobenzoate is a chemical compound composed of a methyl ester group, a bromomethyl group, and a nitrobenzene group. It is used in organic synthesis as a reagent for the introduction of a bromomethyl group onto other molecules. methyl 3-(bromomethyl)-2-nitrobenzoate is also used as an intermediate in the production of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as it is considered to be hazardous, with potential health hazards if not used properly.

Upstream product

• 5471-82-9 methyl 3-methyl-2-nitrobenzoate 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 

Downstream Products

• 1038915-64-8 (3S)-3-[4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidinium chloride 
• 1196713-67-3 2-[4-((3S)-(tertbutoxycarbonyl)piperidin-3-yl)phenyl]-2H-indazole-7-carboxylic acid methyl ester 
• 1038916-11-8 tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate 
• 1038916-08-3 2-{4-[(3S)-1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylic acid 
• 1312106-32-3 18-(nitrobenzylideneamino)phenylpiperidine-1-carboxylate 
• 1246443-44-6 tert-butyl 4-{[3-(methoxycarbonyl)-2-nitrobenzylidene]amino}-4-methylpiperidine-1-carboxylate 
• 952479-61-7 methyl 2-nitro-3-[(phenylimino)methyl]benzoate 
• 952479-62-8 methyl 2-phenyl-2H-indazole-7-carboxylate 
• 1618636-71-7 C₃₂H₃₈N₈O₅ 
• 1618636-70-6 C₁₇H₂₅N₅O₄ 
• 1618636-69-3 C₈H₇N₃O₃ 
• 1618636-68-2 C₉H₉N₃O₃ 
• 253120-48-8 methyl 2-amino-3-(hydroxymethyl)benzoate 
• 1331954-75-6 C₉H₉NO₅ 

Relevant articles and documents

Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials

A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies led to identification of a potent inhibitor 19f, 95-fold more potent than the origin

Polyheterocyclic substituted pyrimidines or pyridylamine derivatives Composition and medical application thereof

The invention discloses a polycyclic substituted pyrimidine or pyridine amine derivative, and the structure is shown in a formula (I). The invention further discloses a pharmaceutically acceptable salt of the derivative, a solvate, a stereoisomer, a prodrug, a pharmaceutical composition and and an application thereof in medicine. The compounds of the present invention have significant adenosine A. 2A Receptor and/or adenosine A2B The receptor antagonism activity is very practical.

SINGLE MOLECULE COMPOUNDS PROVIDING MULTI-TARGET INHIBITION OF PARP AND OTHER PROTEINS AND METHODS OF USE THEREOF

The invention relates to compounds useful for inhibiting PARP and at least one other protein and to methods of treating diseases including cancer by administration of a compound(s) of Formula I-V (or pharmaceutically acceptable salts thereof) as defined herein.