132880-98-9

Basic information

• Product Name: Isocalphostin D
• CAS NO: 132880-98-9
• Mol File: 132880-98-9.mol

Chemical Properties

• CAS DataBase Reference: Isocalphostin D(CAS DataBase Reference)
• NIST Chemistry Reference: Isocalphostin D(132880-98-9)
• EPA Substance Registry System: Isocalphostin D(132880-98-9)

Safety Data

• Hazardous Substances Data: 132880-98-9(Hazardous Substances Data)

Upstream product

• 3686-57-5 2,4-dimethoxy-6-methylbenzoic acid 
• 133363-22-1 7,7'-Bis-((R)-2-hydroxy-propyl)-2,6,2',6'-tetramethoxy-4,4'-bis-methoxymethoxy-[1,1']binaphthalenyl-5,5'-diol 
• 133363-21-0 5,5'-Bis-benzyloxy-7,7'-bis-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-2,6,2',6'-tetramethoxy-4,4'-bis-methoxymethoxy-[1,1']binaphthalenyl 
• 133363-19-6 [(S)-2-(4-Benzyloxy-8-bromo-3,7-dimethoxy-5-methoxymethoxy-naphthalen-2-yl)-1-methyl-ethoxy]-tert-butyl-diphenyl-silane 
• 133363-23-2 [(R)-2-(4-Benzyloxy-8-bromo-3,7-dimethoxy-5-methoxymethoxy-naphthalen-2-yl)-1-methyl-ethoxy]-tert-butyl-diphenyl-silane 
• 133363-18-5 1-Benzyloxy-5-bromo-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalene-2-carbaldehyde 
• 133363-16-3 {1-Benzyloxy-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalen-2-yl}-methanol 
• 133363-17-4 1-Benzyloxy-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalene-2-carbaldehyde 
• 133363-15-2 (S)-10-Hydroxy-7-methoxy-9-methoxymethoxy-3-methyl-3,4,4a,5-tetrahydro-benzo[g]isochromen-1-one 
• 133363-14-1 ethyl 4-methoxy-2-(methoxymethoxy)-6-methylbenzoate 
• 57749-86-7 ethyl 2,4-dimethoxy-6-methylbenzoate 
• 6110-36-7 ethyl everninate 

Downstream Products

• 56974-44-8 isophleichrome 
• 123940-54-5 hypocrellin-B 

Relevant articles and documents

Total synthesis of phleichrome, calphostin A, and calphostin D. Unusual stereoselective and stereospecific reactions in the synthesis of perylenequinones

This report describes the total synthesis of phleichrome, calphostin A and calphostin D - three protein kinase C inhibitory perylenequinones. The present route affords the targets in enantiomerically pure form and represents the first successful approach

Design, synthesis, and investigation of protein kinase C inhibitors: Total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones

The total syntheses of the PKC inhibitors (+)-calphostin D, (+)-phleichrome, cercosporin, and 10 novel perylenequinones are detailed. The highly convergent and flexible strategy developed employed an enantioselective oxidative biaryl coupling and a double

Optically active total synthesis of calphostin D

An optically active total synthesis of calphostin D (1a) through dimerization of the chiral o-naphthoquinone 6 has been accomplished. The mechanism of the dimerization has been shown to be an acid-catalyzed process.

Secondary Mould Metabolites. Part 13. Fungal Perylenequinones: Phleichrome, Isophleichrome, and their Endoperoxides

The helix-shaped, fungal pigment phleichrome has been isomerized to isophleichrome.The axial chirality and absolute configuration of the side-chain carbons of both perylenequinones have been established.Photo-oxidation of both compounds occurs stereospecifically to give their endoperoxides, whose structure and sterochemistry results from a detailed analysis of their n.m.r. spectra.