56974-44-8

Upstream product

• 3686-57-5 2,4-dimethoxy-6-methylbenzoic acid 
• 55018-89-8 2,4-dimethoxy-6-methylbenzoyl chloride 
• 6110-36-7 ethyl everninate 
• 57749-86-7 ethyl 2,4-dimethoxy-6-methylbenzoate 
• 133363-22-1 7,7'-Bis-((R)-2-hydroxy-propyl)-2,6,2',6'-tetramethoxy-4,4'-bis-methoxymethoxy-[1,1']binaphthalenyl-5,5'-diol 
• 133363-21-0 5,5'-Bis-benzyloxy-7,7'-bis-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-2,6,2',6'-tetramethoxy-4,4'-bis-methoxymethoxy-[1,1']binaphthalenyl 
• 133363-19-6 [(S)-2-(4-Benzyloxy-8-bromo-3,7-dimethoxy-5-methoxymethoxy-naphthalen-2-yl)-1-methyl-ethoxy]-tert-butyl-diphenyl-silane 
• 133363-23-2 [(R)-2-(4-Benzyloxy-8-bromo-3,7-dimethoxy-5-methoxymethoxy-naphthalen-2-yl)-1-methyl-ethoxy]-tert-butyl-diphenyl-silane 
• 133363-18-5 1-Benzyloxy-5-bromo-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalene-2-carbaldehyde 
• 133363-16-3 {1-Benzyloxy-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalen-2-yl}-methanol 
• 133363-17-4 1-Benzyloxy-3-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-6-methoxy-8-methoxymethoxy-naphthalene-2-carbaldehyde 
• 133363-15-2 (S)-10-Hydroxy-7-methoxy-9-methoxymethoxy-3-methyl-3,4,4a,5-tetrahydro-benzo[g]isochromen-1-one 

Downstream Products

• 56974-44-8 isophleichrome 
• 123940-54-5 hypocrellin-B 

Relevant academic research and scientific papers

Optically active total synthesis of calphostin D

An optically active total synthesis of calphostin D (1a) through dimerization of the chiral o-naphthoquinone 6 has been accomplished. The mechanism of the dimerization has been shown to be an acid-catalyzed process.

Design, synthesis, and investigation of protein kinase C inhibitors: Total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones

The total syntheses of the PKC inhibitors (+)-calphostin D, (+)-phleichrome, cercosporin, and 10 novel perylenequinones are detailed. The highly convergent and flexible strategy developed employed an enantioselective oxidative biaryl coupling and a double

Total synthesis of phleichrome, calphostin A, and calphostin D. Unusual stereoselective and stereospecific reactions in the synthesis of perylenequinones

This report describes the total synthesis of phleichrome, calphostin A and calphostin D - three protein kinase C inhibitory perylenequinones. The present route affords the targets in enantiomerically pure form and represents the first successful approach

Secondary Mould Metabolites. Part 13. Fungal Perylenequinones: Phleichrome, Isophleichrome, and their Endoperoxides

The helix-shaped, fungal pigment phleichrome has been isomerized to isophleichrome.The axial chirality and absolute configuration of the side-chain carbons of both perylenequinones have been established.Photo-oxidation of both compounds occurs stereospecifically to give their endoperoxides, whose structure and sterochemistry results from a detailed analysis of their n.m.r. spectra.