132898-07-8 Usage
Uses
Used in Pharmaceutical Industry:
2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-F]quinoxaline is used as a mutagen in the pharmaceutical industry for its ability to induce genetic mutations in bacterial systems. This property makes it a valuable tool for studying genetic alterations and their effects on cellular processes.
Used in Research and Development:
In the field of research and development, 2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-F]quinoxaline is utilized as a mutagen for conducting experiments related to DNA repair mechanisms in liver cells. Its mutagenicity allows scientists to investigate the cellular response to DNA damage and the role of DNA repair genes in maintaining genomic stability.
Used in Toxicology Studies:
2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-F]quinoxaline is also employed in toxicology studies to evaluate the potential genotoxic effects of various chemicals and substances. Its mutagenicity in bacterial systems serves as a basis for assessing the genotoxic potential of other compounds, which is crucial for understanding their safety and potential health risks.
Used in Environmental Monitoring:
In environmental monitoring, 2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-F]quinoxaline can be used as a reference mutagen to assess the mutagenic potential of environmental samples. This helps in identifying and quantifying the presence of mutagenic pollutants, which is essential for understanding their impact on ecosystems and human health.
Used in Quality Control:
The mutagenicity of 2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-F]quinoxaline makes it a useful compound for quality control purposes in the chemical and pharmaceutical industries. It can be used to test the effectiveness of safety measures and protocols designed to minimize the risk of exposure to mutagenic substances during the manufacturing process.
Safety Profile
Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 132898-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,8,9 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 132898-07:
(8*1)+(7*3)+(6*2)+(5*8)+(4*9)+(3*8)+(2*0)+(1*7)=148
148 % 10 = 8
So 132898-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H15N5/c1-6-5-9-10(16-8(3)7(2)15-9)11-12(6)18(4)13(14)17-11/h5H,1-4H3,(H2,14,17)
132898-07-8Relevant academic research and scientific papers
Synthesis of Mutagenic Methyl- and Phenyl-substituted 2-Amino-3H-imidazoquinoxalines via 2,1,3-Benzoselenadiazoles
Grivas, Spiros,Tian, Wei,Ronne, Erik,Lindstroem, Stefan,Olsson, Kjell
, p. 521 - 528 (2007/10/02)
2-Amino-3-methyl-3H-imidazoquinoxaline, all its derivatives with 1-4 methyl groups in positions 4, 5, 7 and 8, and 2-amino-3,5-dimethyl-7,8-diphenyl-3H-imidazoquinoxaline have been synthesized from the corresponding 6-methylamino-5-nitroquinoxalines through reduction and cyclization with cyanogen bromide.The quinoxalines were obtained from the appropriate α-dicarbonyl compounds and 4-methylamino-3-nitro-1,2-benzenediamines.The latter were prepared from 4-halo-1,2-benzenediamines via 2,1,3-benzoselenadiazoles.The 7- and 8-phenyl derivatives of 2-amino-3,5-dimethyl-3H-imidazoquinoxaline have been synthesized in a slightly different way.
