132898-87-4Relevant academic research and scientific papers
Variations of the Nature of the Chiral Auxiliary with a Highly Enantioselective Chiral NADH Model
Combret, Yves,Duflos, Jack,Dupas, Georges,Bourguignon, Jean,Queguiner, Guy
, p. 1635 - 1644 (2007/10/02)
Various chiral amine alcohols have been used as chiral auxiliares for a highly enantioselective NADH model.Some of these are new reagents which have been obtained by an enzymic resolution method.
Stereoselectivity of hydrogen transfer with chiral NADH models as a function of configuration and conformation
Combret, Yves,Torche, Jean-Jacques,Ple, Nelly,Duflos, Jack,Dupas, Georges,Bourguignon, Jean,Queguiner, Guy
, p. 9369 - 9382 (2007/10/02)
NADH model compounds bearing chiral amide groups have been synthesized. One of these models, 3, possessed the 1,6-naphtyridinone structure and the key step of its synthesis was a cross coupling reaction which was optimized on the basis of consideration of
Asymmetric Reductions with Freely and Non-freely Rotating Amide Group NADH Models
Combret, Yves,Torche, Jean Jacques,Binay, Patrice,Dupas, Georges,Bourguignon, Jean,Queguiner, Guy
, p. 125 - 128 (2007/10/02)
NADH models with a freely or a non freely rotating chiral amide group have been synthesized and used in the reduction of methyl benzoylformate.The same major enantiomer was obtained in all cases.A blocked reagent bearing a phenylalaninol group as chiral auxiliary allows one to obtain a high e.e.
