138850-44-9

Upstream product

• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 132898-85-2 2-<2-(N-(S)-1-benzylhydroxyethyl)amino>ethyl-nicotinonitrile 
• 138921-62-7 2-<2-(N-(S)-1-benzylhydroxyethyl)amino>ethenylnicotinonitrile 
• 97308-49-1 2-trimethylsilylethynyl-3-pyridinecarbonitrile 
• 132898-81-8 2-Ethynylnicotinonitrile 
• 132898-87-4 6-<(S)-1-benzylhydroxyethyl>-5-oxo-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 74-88-4 methyl iodide 

Downstream Products

• 132898-89-6 1-Methyl-6-<(S)-1-benzylhydroxyethyl>-1,4,5,6,7,8-hexahydro-5-oxo-1,6-naphthyridine 

Relevant academic research and scientific papers

Stereoselectivity of hydrogen transfer with chiral NADH models as a function of configuration and conformation

NADH model compounds bearing chiral amide groups have been synthesized. One of these models, 3, possessed the 1,6-naphtyridinone structure and the key step of its synthesis was a cross coupling reaction which was optimized on the basis of consideration of

Asymmetric Reductions with Freely and Non-freely Rotating Amide Group NADH Models

NADH models with a freely or a non freely rotating chiral amide group have been synthesized and used in the reduction of methyl benzoylformate.The same major enantiomer was obtained in all cases.A blocked reagent bearing a phenylalaninol group as chiral auxiliary allows one to obtain a high e.e.