13291-43-5Relevant academic research and scientific papers
A novel nickel-catalyzed synthesis of thioesters, esters and amides from aryl iodides in the presence of chromium hexacarbonyl
Iranpoor, Nasser,Firouzabadi, Habib,Etemadi-Davan, Elham,Nematollahi, Arash,Firouzi, Hamid Reza
, p. 6445 - 6452 (2015/08/11)
This study describes our findings on a novel and cheap NiCl2 catalytic system under ligand-free conditions for the efficient thiocarbonylation, alkoxycarbonylation and amidocarbonylation reactions of aryl iodides in the presence of Cr(CO)6 as the solid source of carbon monoxide under air. A variety of aryl iodides tolerated the reaction conditions and structurally different thiols, alcohols and amines were used efficiently. The corresponding thioesters, esters and amides were obtained in good to excellent yield at atmospheric pressure under mild reaction conditions.
1-(2,5-dichlorophenyl)-2,2-bis(methylsulfanyl)vinyl esters as highly efficient chemoselective acylating reagents
Degani,Dughera,Fochi,Serra
, p. 1200 - 1208 (2007/10/03)
1-(2,5-Dichlorophenyl)-2,2-bis(methylsulfanyl)vinyl esters 4f-k were prepared in yields usually greater than 90%, by reacting acyl chlorides with 1-(2,5-dichlorophenyl)-2,2-bis(methylsulfanyl)ethanone enolate. These esters were demonstrated to be excellent chemoselective reagents for the acylation of amines, alcohols, thiols, pyrrole and indole. From all the acylation reactions the dimethyl α-oxo dithioacetal 2d, recyclable for the preparation of esters 4f-k, could be recovered in 90-100% yield.
NEW CONDENSING REAGENTS: THIOPHOSPHORUS COMPOUNDS ACTIVATED BY 2-OXAZOLONE AND 2-BENZOXAZOLINONE HETEROCYCLES
Otsubo, Teruyuki,Matsukawa, Chiyoko,Ishizuka, Tadao,Kunieda, Takehisa
, p. 131 - 134 (2007/10/02)
The thiophosphorus compounds (3-6) activated by 2-oxazolone and 2-benzoxazolinone heterocycles, which have the advantages of high solubility in organic solvents and good preservability, serve well as versatile condensing reagents for one-step formation of amides including β-lactams, esters and thioesters from carboxylic acids.
