1329116-26-8

Basic information

• Product Name: 3-(4-fluorophenyl)-2H-chromene-4-carbonitrile
• Synonyms: 3-(4-fluorophenyl)-2H-chromene-4-carbonitrile
• CAS NO: 1329116-26-8
• Molecular Weight: 251.26
• Mol File: 1329116-26-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)-2H-chromene-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-2H-chromene-4-carbonitrile(1329116-26-8)
• EPA Substance Registry System: 3-(4-fluorophenyl)-2H-chromene-4-carbonitrile(1329116-26-8)

Safety Data

• Hazardous Substances Data: 1329116-26-8(Hazardous Substances Data)

Upstream product

• 14714-50-2 2-hydroxybenzyl cyanide 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 7035-03-2 2-methoxy-benzeneacetonitrile 

Relevant articles and documents

Convenient one-pot synthesis of 3-aryl-2H-chromene- 4-carbonitriles via a tandem O-alkylationknoevenagel condensation

3-Aryl-2H-chromene-4-carbonitriles were synthesized through one-pot tandem reaction of easily available 2-(2-hydroxyphenyl)acetonitrile (1) and 2-bromo-1-arylethanones (2) under the condition of K2CO 3/dioxane. These functionalized chromenes could be useful building-blocks for estrogen receptor ligands and other related heterocycles.