132929-62-5

Upstream product

• 123-75-1 pyrrolidine 
• 927434-10-4 2-bromomethylcyclohex-2-enone 
• 105956-40-9 2-(hydroxymethyl)cyclohex-2-en-1-one 
• 76047-55-7 2--2-cyclohexenone 
• 113526-04-8 2-(nitromethyl)-cyclohex-1-ene-3-one 
• 930-68-7 cyclohexenone 
• 125066-15-1 2-(phenylsulfonylmethyl)cyclohexenone 

Relevant academic research and scientific papers

Transition-metal-free nucleophilic allylic substitutions of Morita–Baylis–Hillman bromides with aliphatic and aromatic amines

A simple protocol for the preparation of functionalized allylic amines under mild, transition-metal-free conditions from the reaction of Morita–Baylis–Hillman (MBH) bromides with amines is described herein. The treatment of the MBH bromides with various amines in the presence of NaI and Et3N in aqueous acetone solution and at room temperature affords the corresponding functionalized allyl amines in moderate to good yields (45–87%). The reaction is rapid and carried out at room temperature.

Regioselective replacement of nitro or sulfonyl group in cyclic α-(nitroalkyl)- or α-(phenylsulfonylalkyl)enones by nucleophiles

Cyclic α-(nitroalkyl)enones and α-(phenylsulfonylalkyl)enones undergo regioselective substitution of the nitro group by relatively soft sulfur, nitrogen and carbon nucleophiles.