132960-12-4

Basic information

• Product Name: N-METHOXY-N,5-DIMETHYLTHIOPHENE-2-CARBOXAMIDE
• Synonyms: N-METHOXY-N,5-DIMETHYLTHIOPHENE-2-CARBOXAMIDE
• CAS NO: 132960-12-4
• Molecular Formula: C₈H₁₁NO₂S
• Molecular Weight: 185.25
• Mol File: 132960-12-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-METHOXY-N,5-DIMETHYLTHIOPHENE-2-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHOXY-N,5-DIMETHYLTHIOPHENE-2-CARBOXAMIDE(132960-12-4)
• EPA Substance Registry System: N-METHOXY-N,5-DIMETHYLTHIOPHENE-2-CARBOXAMIDE(132960-12-4)

Safety Data

• Hazardous Substances Data: 132960-12-4(Hazardous Substances Data)

Upstream product

• 30289-28-2 N-methoxy-N-methylcarbamoyl chloride 
• 31555-59-6 5-methylthiophene-2-carbonyl chloride 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 1918-79-2 2-methylthiophene-5-carboxylic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 123707-26-6 N,N'-dimethoxy-N,N'-dimethyl urea 
• 63762-42-5 2-lithio-5-methylthiophene 

Downstream Products

• 334917-71-4 (5-methyl-thiophen-2-yl)-(1-trityl-1H-imidazol-4-yl)-methanone 
• 56824-74-9 (5-methylthiophen-2-yl)(m-tolyl)methanone 
• 1027664-53-4 (5-methyl-thiophen-2-yl)-(1-trityl-1H-imidazol-4-yl)-methanol 
• 99845-90-6 bis(5-methylthiophene-2-yl) ketone 

Relevant articles and documents

Palladium-catalyzed preparation of Weinreb amides from boronic acids and N-methyl-N-methoxycarbamoyl chloride

(Chemical Equation Presented) A simple protocol for the synthesis of Weinreb benzamides and α,β-unsaturated Weinreb amides through a palladium-catalyzed cross-coupling reaction between organoboronic acids and N-methoxy-N-methylcarbamoyl chloride has been developed. The method is also applicable to the use of potassium organotrifluoroborates. 2010 American Chemical Society.

TACHYKININ RECEPTOR ANTAGONISTS

The present invention relates to selective NK-1 receptor antagonists of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of disorders associated with an excess of tachykinins.

Use of N,N'-Dimethoxy-N,N'-dimethylurea as a Carbonyl Dication Equivalent in Organometallic Addition Reactions. Synthesis of Unsymmetrical Ketones

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