132993-20-5 Usage
Description
1-(3-Nitro-phenyl)-pyrrolidine, with the molecular formula C11H12N2O2, is a pyrrolidine derivative featuring a 3-nitrophenyl group. This unique structure endows the compound with distinctive chemical properties and reactivity, making it a promising candidate for pharmaceutical and organic synthesis applications. Its potential as a building block in the synthesis of complex organic compounds and as a precursor to drug molecules with pharmacological activity highlights its versatility in research and industrial settings.
Uses
Used in Pharmaceutical Industry:
1-(3-Nitro-phenyl)-pyrrolidine is used as a building block for the synthesis of complex organic compounds and drug molecules, leveraging its unique structure and reactivity to contribute to the development of new pharmaceutical agents with potential therapeutic applications.
Used in Organic Synthesis:
1-(3-Nitro-phenyl)-pyrrolidine serves as a precursor in organic synthesis, where its nitrophenyl group imparts specific chemical and physical properties that are of interest in various research and industrial applications, enhancing the synthesis of novel organic compounds with diverse functionalities.
Used in Research Applications:
In research settings, 1-(3-Nitro-phenyl)-pyrrolidine is utilized for studying its chemical properties and reactivity, providing insights into its potential applications in the development of new materials, catalysts, or other chemical entities with specific properties tailored for various uses.
Check Digit Verification of cas no
The CAS Registry Mumber 132993-20-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,9,9 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 132993-20:
(8*1)+(7*3)+(6*2)+(5*9)+(4*9)+(3*3)+(2*2)+(1*0)=135
135 % 10 = 5
So 132993-20-5 is a valid CAS Registry Number.
132993-20-5Relevant articles and documents
Boron trifluoride-mediated synthesis of N-aryl-substituted pyrrolidines from tetrahydrofuran and amines
Hu, Shanshan,Huo, Yan,Wang, Zhihong
, p. 1365 - 1368 (2017)
[Figure not available: see fulltext.] Boron trifluoride-mediated transformation of tetrahydrofuran to corresponding N-aryl-substituted pyrrolidines is conducted under mild reaction conditions, providing a practical synthetic method with reasonable yields. Computational studies confirmed the reaction mechanism involving a fast Lewis acid-assisted ring-opening step, followed by the 7-membered intermediate formation and a ringclosing process as the rate-determining step.
Titanium tetrachloride-mediated synthesis of N-aryl-substituted azacycles from cyclic ethers
Sun, Zunming,Hu, Shanshan,Huo, Yan,Wang, Zhihong
, p. 4363 - 4367 (2017/01/29)
Titanium tetrachloride-mediated transformation of five- and six-membered cyclic ethers to the corresponding N-aryl-substituted azacycles is conducted in moderate to good yields under mild reaction conditions. Computational studies suggested a mechanism involving a Lewis acid-assisted ring-opening, a seven-membered metallacycle intermediate and a ring-closing process facilitated by direct participation of the metal center.
Cadmium(II)-catalyzed C-N cross-coupling of amines with aryl iodides
Rout, Laxmidhar,Saha, Prasenjit,Jammi, Suribabu,Punniyamurthy, Tharmalingam
supporting information; experimental part, p. 395 - 398 (2009/04/10)
Cadmium diacetate dihydrate [Cd(OAc)2·2H2O] in combination with ethylene glycol catalyzes efficiently the C-N cross-coupling of amines with aryl iodides by a benzyne mechanism. Alkyl, aryl and heterocyclic amines are compatible with this system affording the aminated products in high to excellent yield.
