133057-82-6

Basic information

• Product Name: 4-BENZYLOXY-3-FLUORO-BROMOBENZENE
• Synonyms: 1-Bromo-4-benzyloxy-3-fluorobenzene
• CAS NO: 133057-82-6
• Molecular Formula: C₁₃H₁₀BrFO
• Molecular Weight: 281.13
• Product Categories: alkyl bromide|alkyl Fluorine
• Mol File: 133057-82-6.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 345.44 °C at 760 mmHg
• Flash Point: 194.281 °C
• Appearance: /
• Density: 1.445 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BENZYLOXY-3-FLUORO-BROMOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-3-FLUORO-BROMOBENZENE(133057-82-6)
• EPA Substance Registry System: 4-BENZYLOXY-3-FLUORO-BROMOBENZENE(133057-82-6)

Safety Data

• Hazardous Substances Data: 133057-82-6(Hazardous Substances Data)

Usage

General Description

4-BenzylOxy-3-Fluoro-Bromobenzene is a specialized chemical compound. Its chemical formula is C13H11BrFO, signifying that it is a complex organic molecule composed of carbon, hydrogen, bromine, fluorine, and oxygen. 4-BENZYLOXY-3-FLUORO-BROMOBENZENE falls under the category of organobromides as well as phenols and derivatives. 4-BenzylOxy-3-Fluoro-Bromobenzene is commonly used in the field of organic synthesis, serving as an intermediate for a variety of chemical reactions. The presence of the bromine, fluorine, and benzyl groups in this compound contribute to its reactivity and utility in creating more complex chemical entities.

InChI:InChI=1/C13H10BrFO/c14-11-6-7-13(12(15)8-11)16-9-10-4-2-1-3-5-10/h1-8H,9H2

Upstream product

• 367-12-4 2-fluorophenol 
• 100-39-0 benzyl bromide 
• 121219-03-2 4-bromo-3-fluorophenol 
• 368-21-8 2-fluorophenyl phenylmethyl ether 
• 348-61-8 1-bromo-3,4-difluorobenzene 
• 100-51-6 benzyl alcohol 
• 96693-06-0 4-(n-octyloxy)-iodobenzene 
• 2105-94-4 4-bromo-2-fluorophenol 
• 100-44-7 benzyl chloride 

Downstream Products

• 847231-07-6 1-(4-benzyloxy-3-fluorophenyl)-2-methyl-1H-indole 
• 590417-24-6 3-(3-fluoro-4-hydroxyphenyl)propionic acid methyl ester 
• 839694-48-3 7-fluorochroman-6-ol 
• 839694-33-6 2-fluoro-4-(3-hydroxypropyl)phenol 
• 839694-38-1 7-fluoro-1-oxaspiro[4.5]deca-6,9-dien-8-one 
• 143725-37-5 3-Fluoro-4-hydroxy-benzoic acid (S)-1-methyl-heptyl ester 
• 839694-31-4 methyl 3-(4-(benzyloxy)-3-fluorophenyl)acrylate 
• 152552-64-2 4-(benzyloxy)-3-fluorobenzoic acid 
• 133057-83-7 4-benzyloxy-3-fluorophenylboronic acid 

Relevant articles and documents

Fluorinated Radicamine A and B: Synthesis and Glycosidase Inhibition

Fluorinated derivatives of radicamine A and radicamine B have been synthesized from D-arabinose-derived cyclic nitrone. Structure-activity relationship studies showed that glycosidase inhibition of these fluorinated derivatives was significantly influenced by the position of the fluorine atom. C-7 or C-11 fluorination of the aromatic ring decreased α-glucosidase inhibition of the derivatives, whereas C-8 or C-10 fluorination preserved glycosidase inhibitory activities. Fluorinated derivatives of radicamine A and B have been synthesized from D-arabinose-derived cyclic nitrone. Structure-activity relationship studies revealed that glycosidase inhibition of these fluorinated derivatives was significantly influenced by the position of the fluorine atom.

TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE

Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.

[...] compd. mesogene medium

The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula I in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention. Furthermore the invention relates to bimesogenic compounds of formula I inducing a second nematic phase in nematic mixtures that do not show this additional phase without compounds of formula I.