1330745-76-0Relevant academic research and scientific papers
Unsymmetrical Disulfides Synthesis via Sulfenium Ion
Parida, Amarchand,Choudhuri, Khokan,Mal, Prasenjit
, p. 2579 - 2583 (2019)
An umpolung approach for the synthesis of unsymmetrical disulfides via sulfenium ion is reported. In situ generated electrophilic sulfenium ion from electron-rich thiols reacted with second thiols to yield unsymmetrical disulfides. Using an iodine catalyst and 4-dimethylaminopyridine (DMAP)/water as promoter, the target syntheses were achieved in one pot under aerobic condition.
Synthesis of unsymmetrical disulfides: Via PPh3-mediated reductive coupling of thiophenols with sulfonyl chlorides
Liang, Xiao,Pan, Yuanjiang,Wang, Dungai,Xiong, Mingteng,Zhou, Yifeng,Zhu, Heping
supporting information, p. 4447 - 4451 (2020/10/20)
A facile and rapid synthesis of unsymmetrical aryl disulfides using PPh3-mediated reductive coupling of thiophenols with aryl sulfonyl chlorides was described. Good functional group tolerance and scalability were achieved in this strategy. More importantl
Microwave-assisted synthesis of disulfides
Kutuk, Halil,Turkoz, Nalan
experimental part, p. 1515 - 1522 (2011/10/05)
A new microwave-assisted synthesis methodology for the preparation of substituted disulfide derivatives is presented. 4-Substituted sulfenimides were reacted with 4-substituted thiols under neat (to right doughy consistency) conditions in chloroform, with both microwave heating and conventional methods. The resulting 4-substituted disulfide derivatives were obtained at higher yields and in shorter reaction times with microwave heating. Their chemistry was confirmed by 1H-NMR, 13C-NMR, infrared (IR), and elemental analysis.
